Press Release
Your Health in Your Hands: Early Screening and Intervention for Colorectal Cancer Improves People’s Lives
Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer-related deaths. It usually develops slowly over 5-10 years, so early detection can significantly improve treatment outcomes and reduce mortality rates. National screening programs in China, Australia, and the U.S. demonstrate the positive impact of early screening. In July 2024, Australia lowered the screening age from 50 to 45, emphasizing early detection as cancer rates rise among those under 50. Advances in non-invasive tests, such as #BGI’s DNA methylation testing, offer easier and effective options. It is by taking action now and by using the latest tests to identify colorectal cancer at an early stage that can have the greatest impact on people’s lives, today.
China, 9th Aug 2024 – In July 2024 Australia lowered the entry age for its National Bowel Cancer Screening Program from 50 to 45 and became the latest country to recognize that the early detection of colorectal cancer can have a significant impact on people’s lives, especially with cancer rates rising among Australians under 50. From 1982-2014 the incidence of bowel cancer increased 9% for those under 50.
Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer-related deaths. However, colorectal cancer usually develops slowly over a period of 5-10 years which means that early detection can make a very real difference in terms of treatment and mortality rates.
Yet, despite many countries implementing national screening programs, by 2040 the burden of colorectal cancer is projected to increase to 3.2 million new cases and 1.6 million deaths per year representing a 66% and 71% rise in new cases and deaths, respectively, relative to 2020.
More action is needed to persuade people to undergo screening and at an earlier age. However, as BGI identified in its 2024 Global State of Colorectal Cancer Awareness Report, there is a significant gap around the world in awareness of and accessibility to screening programs, with the main barriers to screening being cost and fear.
For many people cancer is a stigma and a highly emotional topic. Most will have known relatives or friends who died from cancer and there is a fear both around being diagnosed with the life-threatening disease and fear of the detection process itself. While colonoscopy is considered the gold standard by doctors for cancer detection, it is invasive and requires both fasting and purging that deters many people from being screened until the disease has developed beyond its early stages, significantly reducing life expectancy rates.
Another widely used test in colorectal screening is fecal immunochemical testing (FIT). This is a stool test that detects hidden blood in the stool which can be a sign of precancerous polyps or colorectal cancer. However, as a screening method FIT has limitations in terms of when the sample can be collected and has a low (11%-29%) detection rate for pre-cancer or early-stage adenomas polyps as well as a high false positive rate.
Advances in detection methods have resulted in a new test that undertakes non-invasive DNA methylation of a stool sample to detect colorectal cancer. Methylation is a biological process in which a small molecule called a methyl group is added to DNA. This can have several impacts including inhibiting the gene, leading to diseases such as a cancers. If the result is positive for biomarkers, a colonoscopy can be performed for more detailed diagnosis. This is easier for people to use and does not have the limitations of FIT testing, nor the expense of a colonoscopy unless one is really needed.
BGI’s COLOTECT test is one of the DNA methylation tests widely available for colorectal cancer. While the screening frequency for FIT is annually, stool DNA tests only need to be performed every three years if the test result is normal. COLOTECT uses multiplex methylation-specific PCR technology to trace abnormal DNA methylation markers in colorectal cancer from stool samples. It has 88% colorectal cancer sensitivity in early detection, which is important since colorectal cancer develops slowly and may not be detected at an early stage when treatment can be more effective.
China has a high rate of bowel cancer with the incidence increasing among those under 50. In 2021-2022 Wuhan implemented a colorectal cancer screening study for people aged 45-60. 98,683 people participated in fecal DNA methylation testing with 4.5% screening positive and leading to colonoscopy diagnosis findings in 2,347 people. This indicates the effectiveness of the fecal DNA methylation test.
In Harbin, an extensive free screening project was launched in March 2024 for 800,000 eligible permanent residents aged 45-64. Powered by the newly established BGI-Heilongjiang Omics Health Axis Intelligent Laboratory (BGI-HL OHA Intelligent Laboratory), the first phase of the screening project uses BGI’s fecal DNA methylation testing to assess the risk of colorectal cancer and advanced adenomas.
Apart from colorectal cancer, this project also screening for hypoglycemia, hyperlipidemia, and hypertension. Large scale public health projects such as these in Harbin and Wuhan are good test cases for the rest of the world on what mass testing can achieve.
National screening programs are certainly helping to improve the detection of colorectal cancer. The U.S. began to promote non-invasive cancer screening much earlier than other countries, and with the introduction of new screening technologies and the continuous improvement of screening coverage, the incidence and mortality rate of colorectal cancer in the U.S. has steadily declined.
Australia’s National Bowel Cancer Screening Program was implemented in 2006, based initially on FIT testing and this has led to the screening age range expanding over time to 50-70 years old and now to 45-74 years old. This has resulted in a drop in mortality from bowel cancer from 44.1/100,000 people in 2006 to 29.8/100,000 people in 2018, and a further decline to 23/100,000 people is expected in 2024.
The expansion of the screening age to 45 years by many countries will undoubtedly bring widespread positive health benefits and help improve overall cancer management and preventative strategies. At the same time, the advances in detection testing also make it more readily acceptable for people to be willing to be tested and earlier detection leads to earlier treatment and a greater likelihood of effective treatments. Together, these advances promise to make colorectal cancer a more manageable condition and much less life-threatening.
The burden on families and societies of cancer can be enormous. Finding a cure is in many ways the holy grail of scientific research. Cancer evolution and development is extensively studied by scientists globally using the latest high-throughput genome sequencing to undertake detailed analysis of DNA coding region mutations leading to colorectal cancer.
In one of the latest studies published recently by Nature, BGI, Uppsala University and other collaborators, undertook the largest integrated genome and transcriptome analysis of colorectal cancer to date, providing ground-breaking insights that could lead to more personalized and effective treatments for colorectal cancer.
While every scientific study leads to an advance in knowledge, it is by taking action now and by using the latest tests to identify colorectal cancer at an early stage that can have the greatest impact on people’s lives, today.
Source:
Lowered eligible age for bowel screening. Australian Government Department of Health and Aged Care. https://www.health.gov.au/our-work/national-bowel-cancer-screening-program/about-the-national-bowel-cancer-screening-program/lowered-eligible-age
Trends in Colon and Rectal Cancer Incidence in Australia from 1982 to 2014: Analysis of Data on Over 375,000 Cases. Cancer Epidemiology, Biomarkers & Prevention. https://aacrjournals.org/cebp/article/28/1/83/71847/Trends-in-Colon-and-Rectal-Cancer-Incidence-in
Colorectal cancer. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/colorectal-cancer
BGI Genomics 2024 Global State of Colorectal Cancer Awareness Report. BGI Genomics. https://www.bgi.com/global/news/bgi-genomics-2024-global-state-of-colorectal-cancer-awareness-report
BGI-HL OHA Laboratory Opens in Harbin, Providing Colorectal Cancer Risk Evaluation for 800,000. BGI Genomics. https://www.bgi.com/global/news/bgi-laboratory-opens-in-harbin-providing-colorectal-cancer-risk-evaluation
Sweden’s Uppsala University and BGI Group Jointly Publish the World’s Largest Multi-Omics Study on Colorectal Cancer. BGI Group. https://en.genomics.cn/en-news-275-6977.html
Media Contact
Organization: BGI Group
Contact Person: Richard Li
Website: https://en.genomics.cn/
Email: Send Email
Country: China
Release Id: 09082415468
The post Your Health in Your Hands: Early Screening and Intervention for Colorectal Cancer Improves People’s Lives appeared on King Newswire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.
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Press Release
The 2024 Chery Group Automotive Design Competition Concludes Successfully: A Journey Bridging Design and the Future
November 4, 2024, the Chery Global Design Center in Wuhu hosted the award ceremony for the 2024 Chery Group Automotive Design Competition. This grand event not only brought together top automotive design talents from around the world but also became a focal point for design enthusiasts, industry experts, and media professionals. As the competition’s exclusive partner, OPSH（OnePen ShangHai)was fully involved, witnessing this remarkable celebration of technology, art, and futuristic imagination.
As Chery Group’s first-ever global automotive design competition, this event attracted worldwide attention with its high level of internationalization and openness. Within just a month, through campus roadshows at universities both domestically and internationally, along with OPSH（OnePen ShangHai)-hosted offline engagement activities, the competition drew over 300 participants from 22 countries, with international students accounting for 50% of the contestants. Spanning Asia, Europe, North America, and Australia, the competition featured participants from 11 prestigious design schools, including China Academy of Art, Luxun Academy of Fine Arts, Hubei Institute of Fine Arts, Tongji University, Chung-Ang University, Yeungnam University, Coventry University, Kyonggi University, and others. This comprehensive participation highlighted the global reach of the event, fostering dialogue among cultures through design and showcasing the diversity and innovation of future mobility.
On the day of the award ceremony, the Chery Global Design Center was transformed into a space where art and technology converged. The unveiling of concept cars and high-fidelity scale models presented a visual feast that combined design aesthetics with technological prowess. The event showcased not only the winning entries but also offered interactive sessions for media and audiences to experience the unique charm of each creation, from design concepts to tangible outputs.
“These entries are more than just sketches or models—they are profound reflections on the future of mobility,” remarked the head of the Chery Automotive Design Center during the ceremony. “From supercars to lunar rovers, flying vehicles to micro-electric cars, each work demonstrates how designers break boundaries with creativity, ingeniously merging technology, aesthetics, and human needs.”
Among the many exceptional submissions, the innovative ideas from rising global design stars stood out. Highlights of the winning entries include:
First Prize:
– Sungjun Park / Chung-Ang University
Second Prize:
– Liu Haoyang/ China Academy of Art
– Junwan Woo/ Yeungnam University
Third Prize:
– Feng Yongqi/ Hubei Institute of Fine Arts
– Hu Zhanpeng/ Tongji University
– Liu Yunfeng/ Luxun Academy of Fine Arts
Excellent Design Awards:
– Joongha Min/ Coventry University
– Yongkyun Lee/ Kyonggi University
In addition, during the 2024 Guangzhou International Auto Show, several of these award-winning models were displayed at the Chery Group booth in Hall 4.2, offering visitors an up-close view of the cutting-edge concepts and inspiring future possibilities.
The 2024 Chery Group Automotive Design Competition was not only a platform to showcase creativity but also an important catalyst for industry inspiration. The participation of students from 11 top universities, spanning China and the world, such as the Central Academy of Fine Arts, Nanjing University of the Arts, and the Royal College of Art, added tremendous value to the competition. From its international lineup of participants to designs that embraced future technologies and sustainability, Chery conveyed its profound understanding and boundless imagination for future mobility through this competition. “This is not just a competition; it’s a starting point,” summarized a Chery Group representative. “We hope to inspire more young talents to bring their dreams and creativity to automotive design, providing breakthrough solutions for the future of transportation.”
Amid applause and cheers, the competition concluded successfully. Yet, this is not the end—it is an invitation to the future. Chery Group plans to expand the competition’s scale, welcoming more emerging design talents from around the globe to this innovative stage. Chery eagerly anticipates another year of vibrant and diverse design works, painting a richer picture for the future of automotive design.
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Unveiling the Ultimate Nile Cruise Experience
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Media Contact:
Nile Cruise Ship
Website: https://nilecruiseship.com
Phone: +20 2 23504930
Email: booking@nilecruiseship.com
Address: 81 Abu Daoud, el Zahery, Nasr City, Cairo Governorate 11856,
Egypt
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Press Release
Santa Coin Ushers in the 2024 Yuletide Season with Festive Promotions and a Legacy of Generosity
Santa Coin, the festive-themed cryptocurrency renowned for its spirit of giving, is delighted to announce a series of engaging promotional activities for the 2024 holiday season. Since its inception in October 2021, Santa Coin has distributed over $5 million in rewards to its holders, solidifying its position as a leader in merging generosity with innovation in the cryptocurrency space.
A Legacy of Festive Generosity
Launched in October 2021, Santa Coin was conceived to infuse the holiday spirit into the digital currency realm. Over the past three years, it has built a robust community of enthusiasts and has rewarded its holders with over $5 million, exemplifying its commitment to generosity and community engagement.
Innovative Features
Santa Coin distinguishes itself with several unique features:
• SantaGPT: An AI-driven tool that generates festive content and provides market insights, enhancing user engagement and information dissemination. • AI-Powered Image Generator: Allows users to create captivating memes and graphics, fostering creativity within the community.
• Commitment to Sustainability and Philanthropy: A portion of Santa Coin’s tokenomics is dedicated to supporting charitable organizations and environmental initiatives, reflecting its dedication to positive global impact. •
2024 Yuletide Promotions
In celebration of the upcoming holiday season, Santa Coin is launching a series of initiatives to engage its community and attract new enthusiasts:
1. Widespread Press Coverage: Collaborations with major cryptocurrency news platforms to highlight Santa Coin’s unique features, ongoing developments, and holiday campaigns, ensuring prominent visibility during the festive period.
2. Community Engagement Through Social Media: Activation of raiding teams to invigorate discussions on platforms like X (formerly Twitter) and Telegram, sharing updates, addressing inquiries, and nurturing a vibrant community spirit.
3. Premium Advertising Placements: Securing strategic visibility through premium ad placements on the Moralis Crypto Ads Marketplace, ensuring prominent exposure to a broader audience of crypto enthusiasts.
4. Trading Competition with a $10,000 Prize Pool: Hosting a trading competition with a generous $10,000 USDT prize pool, offering participants the opportunity to showcase their trading skills and earn substantial rewards.
5. Holiday Meme Contest Offering $5,000 in Prizes: Organizing a Christmas themed meme contest with a total prize pool of $5,000, encouraging community creativity and the spread of festive joy.
Through these initiatives, Santa Coin continues to embody its core mission of giving back while fostering unity among its global community. The 2024 yuletide season promises to be the most vibrant yet for Santa Coin supporters.
About Santa Coin
Santa Coin is a festive-themed cryptocurrency that integrates the joy of the holiday season with innovative blockchain technology. With features like SantaGPT and a commitment to philanthropy, Santa Coin offers a unique and rewarding experience for its holders.
For more information about Santa Coin and its holiday promotions, please visit the official website at https://santacoin.io/.
Follow Santa Coin on Social Media:
• Website: https://santacoin.io/
• SantaGPT: https://santagpt.ai/
• Twitter: https://twitter.com/Santa_Coins
• Telegram Group: https://t.me/santacoingroup
• Telegram Channel: https://t.me/santanewsofficial
• Medium: https://medium.com/@santa.coin
Media Contact:
Crypto Santa, Lead Developer
Contact Information: Telegram – @crypto_santa001
Disclaimer: This press release is for informational purposes only. Cryptocurrency investments carry risk; please conduct thorough research before participating.
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
The 2024 Chery Group Automotive Design Competition Concludes Successfully: A Journey Bridging Design and the Future
Discover Unmatched Elegance: Luxury Nile River Cruises with Expert Egyptologists
Santa Coin Ushers in the 2024 Yuletide Season with Festive Promotions and a Legacy of Generosity
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