Press Release
Your Health in Your Hands: Early Screening and Intervention for Colorectal Cancer Improves People’s Lives
Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer-related deaths. It usually develops slowly over 5-10 years, so early detection can significantly improve treatment outcomes and reduce mortality rates. National screening programs in China, Australia, and the U.S. demonstrate the positive impact of early screening. In July 2024, Australia lowered the screening age from 50 to 45, emphasizing early detection as cancer rates rise among those under 50. Advances in non-invasive tests, such as #BGI’s DNA methylation testing, offer easier and effective options. It is by taking action now and by using the latest tests to identify colorectal cancer at an early stage that can have the greatest impact on people’s lives, today.
China, 9th Aug 2024 – In July 2024 Australia lowered the entry age for its National Bowel Cancer Screening Program from 50 to 45 and became the latest country to recognize that the early detection of colorectal cancer can have a significant impact on people’s lives, especially with cancer rates rising among Australians under 50. From 1982-2014 the incidence of bowel cancer increased 9% for those under 50.
Colorectal cancer is the third most common cancer worldwide and the second leading cause of cancer-related deaths. However, colorectal cancer usually develops slowly over a period of 5-10 years which means that early detection can make a very real difference in terms of treatment and mortality rates.
Yet, despite many countries implementing national screening programs, by 2040 the burden of colorectal cancer is projected to increase to 3.2 million new cases and 1.6 million deaths per year representing a 66% and 71% rise in new cases and deaths, respectively, relative to 2020.
More action is needed to persuade people to undergo screening and at an earlier age. However, as BGI identified in its 2024 Global State of Colorectal Cancer Awareness Report, there is a significant gap around the world in awareness of and accessibility to screening programs, with the main barriers to screening being cost and fear.
For many people cancer is a stigma and a highly emotional topic. Most will have known relatives or friends who died from cancer and there is a fear both around being diagnosed with the life-threatening disease and fear of the detection process itself. While colonoscopy is considered the gold standard by doctors for cancer detection, it is invasive and requires both fasting and purging that deters many people from being screened until the disease has developed beyond its early stages, significantly reducing life expectancy rates.
Another widely used test in colorectal screening is fecal immunochemical testing (FIT). This is a stool test that detects hidden blood in the stool which can be a sign of precancerous polyps or colorectal cancer. However, as a screening method FIT has limitations in terms of when the sample can be collected and has a low (11%-29%) detection rate for pre-cancer or early-stage adenomas polyps as well as a high false positive rate.
Advances in detection methods have resulted in a new test that undertakes non-invasive DNA methylation of a stool sample to detect colorectal cancer. Methylation is a biological process in which a small molecule called a methyl group is added to DNA. This can have several impacts including inhibiting the gene, leading to diseases such as a cancers. If the result is positive for biomarkers, a colonoscopy can be performed for more detailed diagnosis. This is easier for people to use and does not have the limitations of FIT testing, nor the expense of a colonoscopy unless one is really needed.
BGI’s COLOTECT test is one of the DNA methylation tests widely available for colorectal cancer. While the screening frequency for FIT is annually, stool DNA tests only need to be performed every three years if the test result is normal. COLOTECT uses multiplex methylation-specific PCR technology to trace abnormal DNA methylation markers in colorectal cancer from stool samples. It has 88% colorectal cancer sensitivity in early detection, which is important since colorectal cancer develops slowly and may not be detected at an early stage when treatment can be more effective.
China has a high rate of bowel cancer with the incidence increasing among those under 50. In 2021-2022 Wuhan implemented a colorectal cancer screening study for people aged 45-60. 98,683 people participated in fecal DNA methylation testing with 4.5% screening positive and leading to colonoscopy diagnosis findings in 2,347 people. This indicates the effectiveness of the fecal DNA methylation test.
In Harbin, an extensive free screening project was launched in March 2024 for 800,000 eligible permanent residents aged 45-64. Powered by the newly established BGI-Heilongjiang Omics Health Axis Intelligent Laboratory (BGI-HL OHA Intelligent Laboratory), the first phase of the screening project uses BGI’s fecal DNA methylation testing to assess the risk of colorectal cancer and advanced adenomas.
Apart from colorectal cancer, this project also screening for hypoglycemia, hyperlipidemia, and hypertension. Large scale public health projects such as these in Harbin and Wuhan are good test cases for the rest of the world on what mass testing can achieve.
National screening programs are certainly helping to improve the detection of colorectal cancer. The U.S. began to promote non-invasive cancer screening much earlier than other countries, and with the introduction of new screening technologies and the continuous improvement of screening coverage, the incidence and mortality rate of colorectal cancer in the U.S. has steadily declined.
Australia’s National Bowel Cancer Screening Program was implemented in 2006, based initially on FIT testing and this has led to the screening age range expanding over time to 50-70 years old and now to 45-74 years old. This has resulted in a drop in mortality from bowel cancer from 44.1/100,000 people in 2006 to 29.8/100,000 people in 2018, and a further decline to 23/100,000 people is expected in 2024.
The expansion of the screening age to 45 years by many countries will undoubtedly bring widespread positive health benefits and help improve overall cancer management and preventative strategies. At the same time, the advances in detection testing also make it more readily acceptable for people to be willing to be tested and earlier detection leads to earlier treatment and a greater likelihood of effective treatments. Together, these advances promise to make colorectal cancer a more manageable condition and much less life-threatening.
The burden on families and societies of cancer can be enormous. Finding a cure is in many ways the holy grail of scientific research. Cancer evolution and development is extensively studied by scientists globally using the latest high-throughput genome sequencing to undertake detailed analysis of DNA coding region mutations leading to colorectal cancer.
In one of the latest studies published recently by Nature, BGI, Uppsala University and other collaborators, undertook the largest integrated genome and transcriptome analysis of colorectal cancer to date, providing ground-breaking insights that could lead to more personalized and effective treatments for colorectal cancer.
While every scientific study leads to an advance in knowledge, it is by taking action now and by using the latest tests to identify colorectal cancer at an early stage that can have the greatest impact on people’s lives, today.
Source:
Lowered eligible age for bowel screening. Australian Government Department of Health and Aged Care. https://www.health.gov.au/our-work/national-bowel-cancer-screening-program/about-the-national-bowel-cancer-screening-program/lowered-eligible-age
Trends in Colon and Rectal Cancer Incidence in Australia from 1982 to 2014: Analysis of Data on Over 375,000 Cases. Cancer Epidemiology, Biomarkers & Prevention. https://aacrjournals.org/cebp/article/28/1/83/71847/Trends-in-Colon-and-Rectal-Cancer-Incidence-in
Colorectal cancer. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/colorectal-cancer
BGI Genomics 2024 Global State of Colorectal Cancer Awareness Report. BGI Genomics. https://www.bgi.com/global/news/bgi-genomics-2024-global-state-of-colorectal-cancer-awareness-report
BGI-HL OHA Laboratory Opens in Harbin, Providing Colorectal Cancer Risk Evaluation for 800,000. BGI Genomics. https://www.bgi.com/global/news/bgi-laboratory-opens-in-harbin-providing-colorectal-cancer-risk-evaluation
Sweden’s Uppsala University and BGI Group Jointly Publish the World’s Largest Multi-Omics Study on Colorectal Cancer. BGI Group. https://en.genomics.cn/en-news-275-6977.html
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Website: https://en.genomics.cn/
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Country: China
Release Id: 09082415468
The post Your Health in Your Hands: Early Screening and Intervention for Colorectal Cancer Improves People’s Lives appeared on King Newswire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.
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Uncover The Secrets Of The Eyes From Above: Jabari Lamb Invites Readers On An Inspiring Journey Of Triumph, Survival, And Self-Discovery
Ride on a journey of power, survival, and the unbreakable human spirit in the new novel by Jabari Lamb titled “The Eyes From Above.” A Nationwide Release will thereafter tell the story of family, perseverance, and reclaiming one’s identity in a world fraught with danger and hostility.
Track the life of Connie, fighting his way through dangerous waters to uncover long-buried truths about his family’s past, as he evades sinister forces who are determined to stop him at every step. In Charleston, South Carolina, this is the story peeling historical trauma, mythical elements, and an African sense of roots into a bewitching tapestry of history, fantasy, and raw emotion.
There’s that richness of culture and heritage alive through the eyes of his Gullah Geechee perspective: all the trials and triumphs of the African diaspora. He spent time abroad in South Africa, exploring other pockets of the African continent; he weaves a very personal, detailed narrative of African traditions and powerful ancestral connections that should speak to readers from every part of this world.
For high drama or soul-stirring histories, be sure to read “The Eyes from Above” to question what truth is and what is in memory. This book is available in bookstores all over the country and in stores online.
About the Author
A bold, new voice in literature, Jabari Lamb blends history and mythology and his Gullah Geechee heritage in stories hard to forget. This impressive young writer’s novel, The Eyes From Above, explores African roots and displacement based on his journey learning about the Gullah Geechee people, the history of African-Americans, and his trip to South Africa. A voice unique unto his own, Jabari extends the invitation to the reader to consider the fluidity of memory and identity and, indeed, the truth. The Eyes From Above makes its wonderful debut into the literary world.
Media Contact:
Contact Person: Jabari Lamb
Email: Jabarilamb1847@gmail.com
Phone: 770-580-3190
Website: Jabarilamb.com
City: Atlanta
State: Georgia
Country: United States
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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
United States, 17th Oct 2024, – Yijin Hardware, a key player in precision CNC machining, has announced the global expansion of its sheet metal fabrication services. This development is aimed at supporting industries worldwide with high-quality, custom-engineered metal components. By extending services to new markets, Yijin Hardware strengthens its position as a reliable manufacturing partner for sectors that require precise, durable parts, such as automotive, aerospace, and electronics.
Yijin Hardware has a long history of providing precision-engineered components, and its expansion into international markets reflects the company’s response to rising demand for reliable sheet metal fabrication services. The new offerings will include laser cutting, metal bending, welding, and a variety of other fabrication processes, designed to accommodate a wide range of industrial applications.
“Precision and quality have always been at the heart of Yijin Hardware’s operations,” said Gavin Yi, CEO of Yijin Hardware. “The expansion of sheet metal fabrication services is a natural progression in the company’s growth, enabling access to more industries worldwide that require high-performance metal components for their operations.”
The sheet metal fabrication sector has seen increasing demand as industries move towards more complex and custom-engineered solutions. Yijin Hardware’s global expansion is positioned to meet these growing needs by offering scalable services that are capable of handling both small-scale production and larger manufacturing runs. The company’s advanced facilities are equipped with the latest machinery, ensuring that each part meets precise specifications and high-quality standards.
Yijin Hardware has also invested heavily in upgrading its production infrastructure to support the increased demand from international clients. Enhancements in laser cutting, welding, and assembly operations have been key factors in enabling the company to offer a more diverse set of services globally. The ability to handle custom and high-volume orders without compromising on quality is a cornerstone of Yijin Hardware’s service offerings.
“Looking ahead, Yijin Hardware is committed to further advancing its manufacturing capabilities,” Gavin Yi added. “There are plans to introduce more cutting-edge technologies that will enhance both CNC machining and sheet metal fabrication services. These advancements will ensure the company remains well-positioned to address the evolving needs of industries in the future.”
Yijin Hardware’s expanded services will cater to industries with a need for complex, high-precision components, including automotive parts, aerospace structures, and electronic enclosures. With a focus on maintaining strict quality control throughout the production process, the company aims to provide solutions that meet exacting industry standards.
As part of its expansion strategy, Yijin Hardware continues to emphasize innovation and efficiency. These principles are expected to guide the company’s future developments as it explores new manufacturing technologies and methods. The expansion also supports the company’s vision of being a global leader in precision engineering.
For further information about sheet metal fabrication services, please contact Yijin Hardware at +1 626 263 5841 or via email at yijing@yijinsolution.com.
Media Contact
Organization: Yijin Hardware
Contact
Person: Gavin Yi
Website:
http://yijinsolution.com/
Email:
yijing@yijinsolution.com
Country:United States
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United States, 17th Oct 2024, – Yijin Hardware, a well-established provider of custom CNC machining services, has announced its expansion into global markets. The company, recognized for its precision manufacturing capabilities, aims to support international businesses in industries such as aerospace, automotive, electronics, and medical with tailored CNC solutions. This move comes as industries worldwide increasingly require high-quality, custom-manufactured components to meet modern production needs.
Yijin Hardware’s decision to extend its services beyond China reflects its commitment to addressing the needs of a broader range of industries. With years of experience in CNC machining, the company has developed a reputation for delivering reliable and precise parts to a diverse set of clients. The expansion will provide industries worldwide with access to Yijin Hardware’s capabilities, backed by advanced technology and stringent quality control.
Gavin Yi, CEO of Yijin Hardware, commented on the expansion: “This move into international markets represents a significant milestone. Yijin Hardware has always emphasized precision and reliability, and this expansion allows those same standards to be brought to clients around the world. Whether the project involves a small batch of components or a large production run, the company is prepared to meet the exacting standards required by global industries.”
Operating from its facilities in Shenzhen, Yijin Hardware manages the full lifecycle of production, from initial design to final inspection. This comprehensive approach ensures that each project is carefully monitored to meet specific client requirements. Yijin Hardware’s ability to offer customized machining solutions is seen as a key factor in its growth, particularly as companies increasingly seek specialized components for complex applications.
Previously focused primarily on the domestic market in China, Yijin Hardware’s expansion aims to deliver the same level of precision and service to international clients. By positioning itself as a global CNC machining provider, the company plans to strengthen relationships with existing partners while establishing new connections in other regions.
This global expansion comes at a time when demand for CNC machining services is rising due to the increasing complexity of product designs and the need for enhanced precision in manufacturing. As industries continue to evolve, CNC machining remains crucial to ensuring that parts meet exact specifications. Yijin Hardware has embraced this role through continuous investment in advanced equipment and machining techniques.
Looking ahead, Yijin Hardware is also focused on the future of manufacturing and its impact on sustainability. The company plans to explore new methods that reduce material waste and promote more efficient production processes. According to Gavin Yi, “As the company expands globally, attention is focused not only on immediate goals but also on contributing to long-term sustainable manufacturing. CNC machining plays a critical role in reducing waste and improving production efficiency. Yijin Hardware is committed to finding ways to make processes more environmentally friendly, to become a leader in both precision and sustainability.”
Yijin Hardware’s entry into global markets signals a broader shift in its strategy, focusing on serving a more diverse range of industries with its expertise in CNC machining. By offering international clients access to its advanced manufacturing solutions, the company aims to become a trusted partner for businesses looking to streamline production with high-quality, custom-manufactured parts.
For more information about Yijin Hardware’s global CNC machining China, inquiries can be directed via phone at +1 626 263 5841 or by email at yijing@yijinsolution.com.
Media Contact
Organization: Yijin Hardware
Contact
Person: Gavin Yi
Website:
http://yijinsolution.com/
Email:
yijing@yijinsolution.com
Contact Number: 16262635841
Country:United States
The post Yijin Hardware Offers Global CNC Machining Services from China appeared first on
Brand News 24.
It is provided by a third-party content
provider. Brand News 24 makes no
warranties or representations in connection with it.
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Step into a World of Strength and Survival with ‘The Eyes From Above’
Yijin Hardware Delivers High-Quality Sheet Metal Fabrication Services Worldwide
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