Press Release
MAIA Biotechnology’s Unique Telomere Targeting Agent Currently In Clinical Development Shows Promise For The Multi-Billion Dollar Cancer Therapy Market
–News Direct–
By Kyle Anthony, Benzinga
MAIA Biotechnology (AMEX: MAIA) is a cutting-edge biopharmaceutical company dedicated to developing innovative therapies for cancer treatment. The companys mission is to discover, develop and deliver transformative cancer therapies that improve patients' lives worldwide. MAIA Biotechnology envisions a future where cancer is manageable and patients can live longer, healthier lives. The firm is at the forefront of revolutionizing oncology, leveraging advanced scientific research and technological advancements to drive its progress, with the goal of bringing treatments that target cancer's replication mechanism in a more efficacious and less harmful manner than traditional therapies.
Company Background
Founded in August 2018 and headquartered in Chicago, Illinois, MAIA Biotechnology is led by an experienced management team and supported by scientific advisors with extensive drug development experience who are committed to advancing promising agents into human clinical trials. MAIA Biotechnology specializes in telomere-targeting therapies for cancer treatment. As such, the firms current product focus is the development of first-in-class drugs that target proteins that control how cancer cells grow, divide and spread.
MAIA Biotechnology's pipeline includes several promising candidates in various stages of development, but its premier product offering is THIO (6-thio-2-deoxyguanosine), a first-in-class telomere-targeting agent designed to selectively kill telomerase-positive cancer cells, which are present in most human cancers.
The Role Of Telomeres In Cancer
Telomeres play a crucial role in cellular aging and cancer development. Research published by the Dana-Farber Cancer Institute explains that cancer cells often avoid senescence or cell death by rebuilding and maintaining their telomeres despite repeated cell divisions. This is possible because the cancer cells activate an enzyme called telomerase, which adds genetic units to the telomeres to prevent them from shortening to the point of causing cell death. As a result, cancer cells essentially become immortal. Telomerase is silenced in most normal cells but is active in an estimated 85% to 95% of human cancer cells.
Since telomerase is active in cancer cells but not normal cells, it is seen as a promising target for cancer therapy. Due to telomerase inhibition, activity or expression, telomere-targeting drugs might kill tumor cells by allowing telomeres to shrink or by provoking apoptosis, the process of programmed cell death.
By incorporating into telomeres, THIO disrupts their function, leading to cancer cell death. This approach has shown promising preclinical results and has been undergoing clinical trials.
Product Development Pipeline
THIO is MAIA Biotechnologys most advanced product offering, which has shown positive efficacy findings in treating advanced non-small cell lung cancer (NSCLC) in clinical trials. The ongoing clinical trial is testing the hypothesis that lower doses of THIO administered before immune checkpoint inhibitor Libtayo treatment (i.e., stimulation of the immune system to attack cancer cells) would enhance and prolong responses in subjects with advanced NSCLC who did not respond or progress after first-line treatment with a checkpoint inhibitor, a type of drug that blocks proteins called checkpoints that are made by some types of immune system cells such as T cells and some cancer cells. These checkpoints help keep immune responses from being too strong and sometimes can keep T cells from killing cancer cells.
The clinical trial's positive results support THIO's tolerability and safety as an anticancer therapy and a priming immune activator. Treatment with THIO sequenced with Libtayo treatment was found to be well-tolerated in a heavily pre-treated population thus far.
MAIA Biotechnology is also researching other drug treatments, using its expertise in telomere-targeting agents as a foundation. The companys second-generation program aims to discover new compounds with potentially improved specificity toward cancer cells relative to normal cells and potentially increased anticancer activity. This program will allow MAIA Biotechnology to strengthen its patent portfolio over time, which already has five issued patents and 29 applications pending worldwide.
Market Potential and Industry Impact
Research published by Coherent Market Insights estimates the cancer therapy market will be worth $205.10 billion in 2024 and is expected to reach $466.21 billion by 2031. The driving factors behind this growth are the rising occurrence of cancer worldwide and the increasing demand for cancer treatment.
As such, MAIA Biotechnologys THIO addresses a large and growing market. As outlined in their most recent corporate presentation, lung and colon cancer are the first and second most prevalent cancer types globally, respectively, and treating them specifically would generate billions in sales. Given the current opportunity, MAIA Biotechnology will continue to protect its intellectual property while expanding its patent portfolio. Recently, the Food and Drug Administration (FDA) granted a third orphan drug designation (ODD) to THIO as a treatment for glioblastoma; the drug also holds ODDs for hepatocellular carcinoma and small-cell lung cancer. The glioblastoma market is expected to grow from $2.2 billion to $3.2 billion globally in the next three years.
The FDAs ODD program provides multiple incentives to make orphan drug development more financially feasible for companies. These include up to seven years of market exclusivity for the approved orphan drug, up to 20 years of 25% federal tax credit for expenses incurred in conducting clinical research within the U.S., and waiver of Prescription Drug User Fee Act (PDUFA) fees for orphan drugs, a value of approximately $2.9 million in 2021.
Conclusion
MAIA Biotechnologys approach to cancer treatment differentiates it from its peers, potentially placing the company in a unique market position. As incidences of cancer continue to rise globally, drug treatment options, such as THIO, will likely rise in demand. As such, the benefit that MAIA Biotechnology provides and the value proposition the firm espouses will likely continue to have industry resonance.
Featured photo by National Cancer Institute on Unsplash.
Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders.
This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice.
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View source version on newsdirect.com: https://newsdirect.com/news/maia-biotechnologys-unique-telomere-targeting-agent-currently-in-clinical-development-shows-promise-for-the-multi-billion-dollar-cancer-therapy-market-993929137
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DDB Miner, a leading cloud mining platform, has risen to prominence in 2024, providing users with a seamless, reliable, and environmentally sustainable way to mine cryptocurrencies without the need for costly hardware or technical expertise.
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About DDB Miner:
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Audrey
148 Farren Road, Birmingham, West Midlands, United Kingdom
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Your go-to guide for fostering collaboration and fun across corporate teams.
Orlando, FL – 26 October 2024 – Game Show Trivolution, Florida’s premier provider of game show entertainment and team-building events, has released an innovative guide, “101 Team Building Activities to Bring Your Team Together in 2025.” This resource is designed to help companies of all sizes cultivate stronger connections, improve communication, and enhance morale.
The article provides 101 unique activities that bring teams together, ranging from indoor and outdoor activities to icebreakers, virtual solutions, and challenges tailored to large and small groups. With so many actionable ideas, organizations can find inspiration to meet the evolving needs of modern workforces in 2025.
“Team building isn’t just a trend—it’s a necessity,” says Jim Casey, founder of Game Show Trivolution. “This guide is packed with practical, engaging, and creative ideas for any team dynamic, from remote teams to in-person gatherings. It’s about making team building not just effective but enjoyable.”
Highlights from the Guide
The guide breaks down activities into easily navigable sections, making it simple to find the right fit for your team. It includes:
- Icebreaker Activities: Perfect for new teams or kicking off a meeting with energy and connection.
- Indoor and Outdoor Games: Whether the weather is perfect or unpredictable, these activities keep teams engaged.
- Virtual Team-Building Options: Tailored for remote or hybrid teams looking to stay connected and collaborative.
- Problem-Solving Challenges: Boost creativity, critical thinking, and teamwork with engaging puzzles and tasks.
- Fun and Competitive Events: Spark motivation and camaraderie through light-hearted games and contests.
Game Show Trivolution’s Expertise in Engagement
With over a decade of experience providing interactive game shows for clients like Walmart, Marathon Fuel, and Chick-fil-A, Game Show Trivolution is a trusted name in corporate entertainment. Known for creating memorable events with The Big Music Game Show, Smartphone Trivia Game Show, and The Insight Game Show, the company has helped thousands of teams connect, engage, and thrive.
The guide, “101 Team Building Activities for 2025,” builds on this legacy by offering businesses actionable tools to create stronger teams in any setting—whether on-site, virtual, or at a corporate retreat.
Get the Guide Today
To explore the full range of team-building activities and discover how Game Show Trivolution can elevate your next corporate event, visit Game Show Trivolution.
About Game Show Trivolution
Game Show Trivolution specializes in high-energy, interactive game shows and team-building events for corporate groups, private parties, and community gatherings. Based in Orlando, FL, the company serves clients nationwide, delivering tailored entertainment experiences designed to inspire collaboration and fun.
For media inquiries, please contact:
Jim Casey
Founder, Game Show Trivolution
Phone: 813-892-8453
Email: jim@floridagameshow.com
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Press Release
THETAbase.fun: The Ultimate Platform for Shorting Memecoins and Shtcoins Has Launched THTA Token
Los Angeles, CA, United States, 26th Nov 2024 – The memecoin market is notorious for its wild swings, viral hype cycles, and occasional rug pulls. While some investors ride the waves of popularity to massive gains, others are keen to capitalize on the inevitable crashes that follow. Enter THETAbase.fun, the cutting-edge platform designed to rival dumpy.fun, offering a robust marketplace for shorting memecoins and shitcoins destined for zero.
And now, THETAbase has announced the launch of their very own token, $THTA!
What is THETAbase.fun?
At its core, THETAbase.fun is a platform that lets investors take a bearish stance on popular cryptocurrencies. If you’ve ever looked at a hyped-up token and thought, “That’s going to crash,” THETAbase gives you the tools to turn that prediction into profit.
Shorting works by selling borrowed tokens with the intent of repurchasing them at a lower price later. The difference between the sell price and the repurchase price represents your profit—provided the token’s value has indeed decreased. This strategy has long been a staple in traditional finance, but THETAbase brings it to the fast-paced, unpredictable world of memecoins and shitcoins.
The dApp goes live on December 2, 2024.
Markets Available for Shorting
THETAbase.fun offers shorting opportunities across several key networks:
- Solana (SOL): A high-performance blockchain with an ecosystem brimming with memecoins.
- Tron (TRX): Known for its scalable architecture and token-rich environment.
- Base: Coinbase’s Layer 2 solution, home to numerous speculative projects.
Plans are already in motion to expand the available markets to include:
- SUI: A rising Layer 1 network known for its focus on scalability.
- Ton: Telegram’s blockchain project gaining traction in the crypto space.
- Kaspa: A unique proof-of-work network that’s been catching the eye of miners and developers alike.
THETAbase.fun will also integrate Dex Screener’s Moonshot launchpad, enabling users to short the hottest new tokens immediately after launch.
How Token Listings Work
To ensure quality and relevance, tokens are listed on THETAbase.fun based on popularity and liquidity. Users can vote to prioritize their favorite tokens for shorting, creating a dynamic marketplace driven by the community.
In the future, the platform plans to roll out permissionless listings, allowing any token to be listed from day one. This feature will empower traders to act quickly on new opportunities without waiting for centralized approval.
Introducing $THTA: The Official Token of THETAbase.fun
To take the platform to the next level, THETAbase.fun is launching its very own utility token, $THTA. This token will serve as the backbone of the ecosystem, offering holders exclusive benefits such as:
- Fee Discounts: Use $THTA to pay for trading fees and enjoy reduced costs.
- Staking Rewards: Stake $THTA to earn passive income and unlock additional perks.
- Community Governance: Influence the platform’s future by voting on new features, token listings, and network expansions.
By holding $THTA, users not only gain financial advantages but also become part of the driving force behind THETAbase’s growth and innovation.
Why Choose THETAbase.fun?
THETAbase.fun is designed for crypto enthusiasts who want to take full advantage of market volatility. Unlike traditional crypto trading platforms that focus solely on buying and holding, THETAbase empowers users to profit from the inevitable downturns of overhyped projects.
Here’s what sets THETAbase apart:
- Advanced Shorting Tools: A seamless interface for short selling that’s easy to use, even for crypto newcomers.
- Expanding Market Access: With multiple networks and tokens available, traders have endless opportunities.
- Community-Driven Listings: Users can vote for the tokens they want to short, ensuring the platform reflects market demand.
- Permissionless Listings (Coming Soon): The future of THETAbase lies in its ability to offer decentralized, automated token listings.
How to Get Started
Using THETAbase.fun is straightforward. Here’s how to dive in:
- Connect Your Wallet: Start by linking your wallet to the platform to access available markets.
- Choose a Token: Browse the list of tokens available for shorting, or vote to prioritize a new one.
- Open a Short Position: Borrow the token, sell it, and wait for the price to drop.
- Close Your Position: Repurchase the token at the lower price, repay the loan, and pocket the difference as profit.
The Future of THETAbase.fun
THETAbase.fun is more than just a shorting platform—it’s a new way to approach the speculative world of memecoins and shitcoins. By giving users the tools to profit from market crashes, THETAbase introduces balance and sophistication to an ecosystem often driven by hype alone.
As new networks and tokens are added, and permissionless listings become a reality, THETAbase.fun is poised to become the go-to platform for savvy crypto traders looking to bet against the bubble. Whether you’re a seasoned investor or a curious newcomer, THETAbase.fun is your ultimate tool to turn bearish predictions into tangible profits.
Visit THETAbase.fun Today
Ready to start shorting the memecoin market? Visit THETAbase.fun and join the next wave of innovative crypto trading. Your profits are waiting.
Buy $THTA Token Today
PLEASE VISIT THETAbase’s Socials & Follow Their BUY Links To Ensure You’re Buying The Correct $THTA Token!
Buy $THTA: https://thetabase.fun/
Telegram: https://t.me/THETAbase
Twitter: https://twitter.com/THETA_base
Media Contact
Organization: THETAbase
Contact Person: Armani Luciano
Website: https://THETAbase.fun
Email: Send Email
City: Los Angeles
State: CA
Country: United States
Release Id: 26112420407
The post THETAbase.fun: The Ultimate Platform for Shorting Memecoins and Shtcoins Has Launched THTA Token appeared on King Newswire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.
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