Press Release
China Medical System: First Prescriptions for Innovative Drug Lumeblue® Issued in China
SHENZHEN, CHINA – On 6 December, China Medical System Holdings Limited (“CMS” or the “Group”) is pleased to announce that the first prescriptions for the innovative drug Lumeblue® (Methylthioninium Chloride Enteric-coated Sustained-release Tablets) (the “Product”) have been issued in China, which marks that the first oral methylthioninium chloride enteric-coated sustained-release tablets in China has officially entered clinical application. The Product is indicated for enhancing visualization of colorectal lesions in adult patients undergoing screening or surveillance colonoscopies.
Lumeblue® is an oral diagnostic drug that uses patented multi-matrix (MMXTM) technology to deliver active substances directly to the colon and release them locally in a controlled manner. As an enhancer dye, the Product increases the contrast between colorectal lesions and healthy mucosa. The results of the Phase III clinical trial in China show that the Product can significantly improve the detection rate of non-polypoid colorectal lesions (the primary endpoint of the study), leading to an improved detection rate of dangerous lesions such as non-polypoid adenomas (the secondary endpoint)[1]. In addition, the Product can be taken during the bowel preparation step, ensuring that colorectal staining is completed by the time colonoscopy is conducted. This not only enhances the detection rate of colorectal lesions but also potentially simplifies the colonoscopy procedure, making the examination more efficient and improving the screening benefits.
According to the diagnosis and treatment data of the Digestive Endoscopy Branch of the Chinese Medical Association, approximately a total of 28 million gastroenteroscopies were completed nationwide in 2012, including 5.83 million colonoscopies. In 2019, approximately 38.73 million gastroenteroscopies were completed nationwide, an increase of 34.62% compared with 2012[2]. The Expert consensus on the early diagnosis and treatment of colorectal cancer in China (2023 edition) recommends colorectal cancer screening for individuals aged 40 to 74[3]. Based on the China Statistical Yearbook (2023), the total population of this age group in China is 643.36 million[4]. With the popularization of early colorectal cancer screening in China, the number of colonoscopies performed is expected to have significant growth potential in the future. Early diagnosis and removal of lesions are crucial for prevention. Lumeblue® provides an innovative solution for colorectal disease screening and management in response to this growing demand.
The Product has been approved by the European Medicines Agency (EMA) to be commercialized in the European Union under the trade name Lumeblue® in August 2020. The Group obtained an exclusive license for the Product from Cosmo Technologies Ltd., a fully-owned subsidiary of Cosmo Pharmaceuticals NV, on 3 December 2020. Following its approval in China in June 2024, CMS worked collaboratively across its business segments to ensure the rapid importation of the first batch of products. The Group has also actively leveraged its existing gastroenterology portfolio and resources to orderly advance the commercialization and academic promotion of Lumeblue®, facilitating its successful prescriptions launch in China.
With this milestone, CMS’s five innovative drugs have been successfully approved in China and fully entered clinical application. This achievement demonstrates the Group’s ongoing capability of innovation transformation, while reflecting CMS’s commitment to focusing on medical value and fulfilling its corporate social responsibility. Looking ahead, CMS will continue to be patients-centered, efficiently advancing the clinical development and commercialization of innovative products. The Group is dedicated to improving the accessibility and affordability of innovative drugs, benefiting a broader patient population.
About CMS
CMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.
CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.
CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development of its advantageous specialty fields and expand business boundaries. While strengthening the competitiveness of the cardio-cerebrovascular/gastroenterology business, CMS independently operates its dermatology and medical aesthetics business, and ophthalmology business, aiming to gain leading positions in specialty therapeutic fields, whilst enhancing the scale and efficiency. At the same time, CMS has expanded its business territory to the Southeast Asian market, striving to become a “bridgehead” for global pharmaceutical companies to enter the Southeast Asian market, further escorting the sustainable and healthy development of the Group.
References:
CMS Disclaimer and Forward-Looking Statements
This press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.
This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.
Media Contact
Brand: China Medical System Holdings Ltd.
Contact: CMS Investor Relations
Email: ir@cms.net.cn
Website: https://web.cms.net.cn/en/home/
Source: China Medical System Holdings Ltd.
- The results of the Product’s Phase III clinical trial in China were published and are available at: https://web.cms.net.cn/en/2022/12/positive-results-for-china-phase-iii-c…
- Data from the Digestive Endoscopy Branch of the Chinese Medical Association
- Early Diagnosis and Treatment Group of the Chinese Society of Oncology. “Expert Consensus on Early Diagnosis and Treatment of Colorectal Cancer in China (2023 Edition).” Chinese Medical Journal, 2023, 103(48): 3896-3908. DOI: 10.3760/cma.j.cn112137-20230804-00164
- National Bureau of Statistics. (2023). China Statistical Yearbook 2023. Retrieved from https://www.stats.gov.cn/sj/ndsj/2023/indexch.htm
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
6C666.com, Inc. Engages in Strategic Talks with Leading Financial Institutions to Accelerate Global Market Expansion
Brasília, Brazil — Global financial entertainment service platform 6C666.com, Inc. has announced that it is engaging in strategic discussions with multiple top-tier financial institutions to further accelerate its global market expansion plans. This initiative marks a significant step in the company’s internationalization efforts and injects new momentum into its overall competitiveness in the global entertainment and financial services industries.
Founded in 2021 in the United States, 6C666.com, Inc. holds comprehensive business qualifications and currently operates in eight countries, covering areas such as online gaming and video streaming. As an industry-leading platform, the company has rapidly gained global recognition through its efficient and secure transaction system and deep understanding of user needs, establishing itself as a key player in the financial entertainment sector.
Strengthening Global Partnerships
The core objective of these strategic discussions is to establish long-term partnerships with leading financial institutions, leveraging professional financial services and resources to further enhance security systems and improve the global user experience. The CEO of 6C666.com, Inc. stated:
“Globalization is a key direction for our future development. Collaborating with top financial institutions will enable us to better serve users worldwide while enhancing our overall operational efficiency and market competitiveness.”
Recognizing the dual importance of user experience and market reach in an increasingly competitive international landscape, 6C666.com, Inc. aims to achieve breakthroughs in the following areas through its partnerships with financial institutions:
- Strengthening data security and risk management
- Expanding and optimizing localized services
By leveraging the expertise of financial institutions, 6C666.com, Inc. is committed to providing an enhanced experience for users worldwide.
Entry into the Brazilian Market
As part of its global expansion strategy, 6C666.com, Inc. has officially entered the Brazilian market. Through partnerships with local institutions, the company aims to provide a broader range of products and services, contributing to economic growth and job creation in Brazil. The platform will focus on promoting video streaming and online gaming services, attracting more users and creating additional revenue opportunities through flexible collaboration models.
Commitment to Corporate Social Responsibility
While expanding its business, 6C666.com, Inc. places high importance on corporate social responsibility. As part of its global expansion efforts, the company integrates sustainable development principles into all new market initiatives, supporting local social projects and creating long-term value for communities.
A Milestone in Globalization Strategy
This strategic engagement with top financial institutions marks a significant milestone in 6C666.com, Inc.’s globalization journey. By enhancing technology, services, and market strategies, the company is dedicated to building a more efficient, fair, and secure financial entertainment platform, delivering greater value to users worldwide, and setting a new industry benchmark.
As globalization accelerates, the future of 6C666.com, Inc. is highly anticipated.
Company Name: 6C666.com, Inc.
Website: https://6c666.com
Media Contact
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
Scottsdale Jazz Festival to celebrate International Jazz Day and honor Quincy Jones
RnR featuring Rick Braun & Richard Elliot Early Bird Tickets are Now on Sale at scottsdalejazzfest.org. The duo RnR is among the performers at the Scottsdale Jazz Festival on April 26.
SCOTTSDALE, Ariz. — Mark your calendars for an unforgettable evening of music, culture and community as the Scottsdale Jazz Festival returns on Saturday, April 26, 2025, at Scottsdale Civic Center.
Now in its 14th year, the Scottsdale Jazz Festival aligns with UNESCO’s International Jazz Day, this time paying a special tribute to legendary musician and producer Quincy Jones, who died in November. Organized under the visionary leadership of William “Doc” Jones, the festival continues to cement Scottsdale’s reputation as a vibrant cultural destination.
“Several years ago, at the request of the legendary Herbie Hancock, I founded the Scottsdale Jazz Festival to support UNESCO’s International Jazz Day,” Jones said. “Our mission has always been clear: to unite our state around this incredible genre and celebrate its rich history and cultural significance.”
The Arizona Legislature has officially proclaimed April as Jazz Appreciation Month and recognized April 30 as International Jazz Day.
Set against the verdant backdrop of Scottsdale Civic Center, this year’s festival promises to be a spectacular celebration of jazz in all its forms. Enthusiasts will experience a dynamic lineup, featuring celebrated artists, such as Richard Elliot and Rick Braun, who will perform together as the electrifying duo RnR. Known for their signature sounds and showmanship, they are sure to deliver a thrilling experience for the audience.
Dan Pinson, a woodwind master and music educator, will also appear at the festival with his All-Star Band, featuring David Baradic, a former pianist with the Quincy Jones Orchestra, two-time Grammy winning bassist Mel Brown and John Herrera, a Grammy-nominated producer and drummer.
“We’ll perform songs from Quincy Jones and David Sanborn, one of Quincy’s frequent collaborators,” Pinson said. “I hope you’ll join us for a day of great music from some stellar artists!”
The stage will also welcome Carlos Rivas Y Mex-sal, featuring Luisito Rosario, and Nayo Jones of the Nayo Jones Experience, whose soulful voice and captivating presence have frequently dazzled Scottsdale audiences.
This year’s festival is the first in a groundbreaking partnership between the Scottsdale Jazz Festival and Scottsdale Arts. This collaboration is set to bring an even greater level of sophistication and excellence to the event, building on the festival’s history of success.
“For almost a decade, Scottsdale Arts and the Scottsdale Civic Center campus have hosted this important annual event,” said Dr. Gerd Wuestemann, president and CEO of Scottsdale Arts. “We are thrilled to have taken this partnership to the next level by joining forces with Doc Jones and working together to build Scottsdale Jazz Festival into a major destination event for music and jazz lovers from around the Valley, the Southwest and beyond.”
The Scottsdale Jazz Festival has become one of the most anticipated cultural events in the region, drawing a diverse audience from across Arizona, Canada and Mexico. Over the years, it has consistently sold out, with last year’s festival turning away countless attendees at the gates. The event not only showcases world-class jazz performances, but it also fulfills a key objective for the City of Scottsdale: extending the shoulder period of tourism after Spring Training.
Beyond its entertainment value, the festival has a deeply rooted commitment to community enrichment. A cornerstone of its mission is to inspire young people to learn, play and appreciate jazz. Through grassroots efforts led by Doc Jones and community supporters like jeweler Alfredo Molina and Don Fenstermaker, the Scottsdale Jazz Festival has become a symbol of cultural pride and artistic innovation.
Unlike commercially driven festivals, the Scottsdale Jazz Festival is a grassroots-organized event, fueled by passion and a desire to make jazz accessible to everyone. The festival’s history of success is a testament to its organizers’ dedication and vision and the Scottsdale community’s unwavering support.
Attendees will experience diverse jazz styles, from Latin and blues to New Orleans and contemporary sounds. The outdoor setting at the Scottsdale Civic Center will provide the perfect ambiance for this immersive cultural experience as the festival continues to honor the rich legacy of jazz while creating new opportunities for connection and celebration.
“Jazz is more than just music; it reflects our national identity and creativity,” Jones said. “However, its presence in our communities is dwindling, and we must act now to ensure its revival. The Scottsdale Jazz Festival has worked tirelessly to bring together musicians, educators and fans from all walks of life to honor and promote jazz in Arizona.”
Tickets are expected to sell out quickly, so don’t miss your chance to be part of this extraordinary event. Visit ScottsdaleJazzFest.org or call 480-499-8587 for tickets and event information. Scottsdale Civic Center is located at 7380 E. 2nd Street, Scottsdale, AZ 85251.
The Scottsdale Jazz Festival thanks the following 2025 sponsors: Yrefy, LLC (Title); Molina Fine Jewelers; City of Scottsdale; Crescent Crown; Arizona Informant; Fearless Creative; and Scottsdale City Lifestyle.
INTERNATIONAL JAZZ DAY AZ FOUNDATION
For 12 years, the International Jazz Day AZ Foundation, a 501(c)(3) organization, has partnered with UNESCO and Herbie Hancock’s global International Jazz Day to promote jazz as a vital aspect of America’s cultural heritage. Led by William “Doc” Jones, the organization’s commitment to this cause seeks to engage and unify the state of Arizona in celebrating International Jazz Day. Scottsdale is Arizona’s host city for this annual celebration with the Scottsdale Jazz Festival.
SCOTTSDALE ARTS
Through its dynamic partnership with the city of Scottsdale, the nonprofit Scottsdale Arts creates diverse, inspired arts experiences and outreach opportunities for the community while fostering active engagement with the arts among individuals, businesses, educational institutions and government agencies. Since its founding in 1987, Scottsdale Arts has grown into a regionally and nationally significant, multidisciplinary arts organization, offering an exceptional variety of programs for both residents and visitors through Scottsdale Center for the Performing Arts, Scottsdale Museum of Contemporary Art, Scottsdale Public Art, Scottsdale Arts Learning & Innovation, Canal Convergence and Civic Center LIVE.
Youtube Channel Link: https://www.youtube.com/shorts/bC7dxUJtwFc
MEDIA: For interviews, photos or additional information, please contact:
Alicia Haygood
Marketing Manager
International Jazz Day AZ Foundation
Email: Alicia@Michelle.media
Phone: 770-827-0844
Brian Passey
Senior Communications Manager
Scottsdale Arts
Email: BrianP@ScottsdaleArts.org
Phone: 480-874-4626
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Press Release
Shakira Lasisi: A Transformative Leader in Civil Rights Advocacy and Workplace Inclusion
Washington, DC– In a world where equity and fairness remain critical yet challenging ideals, Shakira Lasisi emerges as a transformative leader, bridging the realms of civil rights advocacy and human resources consulting. As a dedicated civil rights activist, Diversity, Equality, and Inclusion (DEI) Officer, and HR Executive, Shakira is reshaping narratives around diversity, inclusion, and anti-discrimination with her expertise, passion, and unwavering commitment to justice.
A Journey Fueled by Education and Experience
Shakira’s remarkable journey is grounded in a strong academic foundation. She earned her Bachelor’s degree in Political Science from Temple University, where she first developed her passion for advocacy and policy reform. Recognizing the importance of understanding human behavior and psychology in fostering inclusive environments, she pursued a Master’s degree in Psychology from Walden University.
Additionally, Shakira honed her professional skills with a Human Resources certificate specializing in Diversity and Inclusion.
These qualifications empower Shakira to approach her work with a nuanced understanding of the systemic challenges individuals face, both within society and the workplace. She has cultivated a unique perspective that combines legal advocacy, policy development, and people-centered strategies to create impactful change.
Bridging Activism and Corporate Strategy
As an HR Executive and DEI Officer, Shakira’s mission is clear: to foster workplaces where diversity is celebrated, inclusion is prioritized, and discrimination is eradicated. Her work spans developing equitable hiring practices, training leadership teams on unconscious bias, and establishing organizational cultures rooted in respect and understanding.
“Inclusion is not just a checkbox or a corporate trend—it’s a moral and organizational imperative,” Shakira explains. “When employees feel valued for their unique perspectives and experiences, organizations thrive. My goal is to ensure that no one is left behind.”
Shakira’s civil rights activism is an extension of her professional endeavors. As a proud member of the NAACP, she tirelessly advocates for marginalized communities, leveraging her voice to address systemic inequities and challenge discriminatory practices. Whether through public speaking, community organizing, or policy reform, Shakira stands at the forefront of the fight for justice.
A Vision for Lasting Impact
Through her work, Shakira has become a trusted voice and advisor for organizations seeking to align their values with meaningful action. Her ability to weave together the complexities of legal advocacy, organizational psychology, and human resources has positioned her as a thought leader in both the public and private sectors.
Her initiatives focus on:
Legal Advocacy: Collaborating with legal teams to ensure compliance with anti-discrimination laws and promoting fairness in employment practices.
Diversity and Inclusion Training: Educating employees and leadership teams on cultural competence, unconscious bias, and inclusive communication.
Policy Development: Crafting actionable policies that address inequities and promote transparency and accountability.
Community Engagement: Partnering with organizations and stakeholders to create opportunities for underrepresented groups and amplify marginalized voices.
Shakira’s Call to Action
Shakira’s impact extends beyond the workplace; she envisions a world where diversity is embraced and equity is the norm. Her work challenges individuals and organizations to rethink outdated practices and take bold steps toward creating truly inclusive environments.
“For me, this work is personal,” Shakira reflects. “I’m driven by the belief that everyone deserves equal access to opportunities, dignity, and respect. When we uplift one another, we create stronger, more resilient communities and workplaces.”
Get Involved
To learn more about Shakira Lasisi’s work, request her expertise as a consultant, or book her for speaking engagements, please contact 609-200-9037 or kira@xmsmanagement.info
About Shakira Lasisi
Shakira Lasisi is a Civil Rights Activist, Human Resources Executive, and Diversity, Equality, and Inclusion Officer with a focus on legal advocacy, workplace anti-discrimination, and fostering inclusive cultures. A member of the NAACP, Shakira holds a Bachelor’s degree in Political Science from Temple University, a Master’s degree in Psychology from Walden University, and an HR certificate specializing in Diversity and Inclusion. Her mission is to create equitable environments where everyone has the opportunity to thrive.
About Author
Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
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