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PathAI Expands Portfolio of AI-Powered Products, Announcing PathExplore IOP and IHC Explore Ahead of ASCO 2024

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–News Direct–

PathAI, a global leader in AI-powered pathology, unveiled two novel AI products, PathExplore Immuno-Oncology Profiling (IOP) and IHC Explore1 to empower cancer drug developers and clinical researchers with AI-powered insights. The product pairing provides unprecedented single-cell and spatial resolution of the tumor microenvironment from routine pathology samples to facilitate biomarker discovery and deeper understanding of treatment response for the next generation of cancer therapeutics. The expansion of the Explore portfolio comes at a time when AI-pathology is experiencing accelerated large-scale adoption across the diagnostic and biopharma industries.

As cancer rates continue to rise, the demand for advanced precision medicine tools that provide accurate biological insights has never been greater. Our mission to make a difference in patient lives is unwavering, and these new products showcase our commitment to providing researchers with the tools they need to make meaningful advancements in cancer research, treatment and care, said Andy Beck, PathAI CEO. We're thrilled to introduce these two groundbreaking products ahead of the American Society of Clinical Oncology annual meeting.

PathExplore IOP: H&E-Based Immune Phenotyping

The composition of the tumor immune microenvironment plays a crucial role in characterizing tumors likely to respond to immunotherapy. PathExplore IOP expedites characterization of immune phenotypes by quantifying tumor infiltrating lymphocytes (TILs) and their spatial distribution using routine hematoxylin and eosin (H&E) samples. With this new product, researchers have the ability to quantify TIL spatial arrangements within tumor core and periphery, and gain insights around the samples immune inflamed, desert, or excluded characteristics.

PathExplore IOP was designed specifically to quantify patterns of immune infiltration characteristic of a strong immune response, and ultimately improved patient survival. Immune infiltration has been previously shown to be prognostic of positive outcomes, however; standardized and scalable approaches for investigating these phenotypes remained elusive.

PathExplore IOP illustrates the power of AI by visually interrogating the dynamics between cancer cells and immune cells with unparalleled resolution for highly accurate and efficient immune phenotype classification, said Benjamin Glass, VP of Product & Translational Research. Researchers can now access insights at scale to better inform biomarker strategies for patient stratification and mechanisms of response and resistance.

PathExplore IOP will be featured in a poster presentation at the upcoming ASCO 2024 meeting, demonstrating the products application for stratification of patient response to checkpoint inhibitors in non-small cell lung cancer.

IHC Explore: AI-Powered Biomarker Quantification

Immunohistochemistry (IHC) is a widely utilized approach for identifying biomarkers unique to certain cancers, informing treatment strategies, measuring prognosis, and patient classification for clinical trials. IHC scoring in the early clinical settings can be time-consuming, subjective, and low-resolution. Especially in early stage biomarker development, defining an optimal scoring system for a novel IHC assay can be complex. IHC Explore fills a need for spatial quantification of IHC biomarkers in single-cell resolution with broad target compatibility.

IHC Explore provides a panel of standardized and structured features that quantify IHC stain abundance within and around cells of the tumor microenvironment, enabling drug developers to build biomarker scoring strategies from scratch for most IHC stains and to precisely find those patients most responsive to treatment. PathAIs partnership with Roche streamlines the translation of these AI insights and scoring strategies into companion diagnostic development.

Drawing on our advanced computational pathology expertise, we're extending the impact of our Explore product suite, which enables us to seamlessly support AI-powered assay development, said Hisani Madison, VP of Precision Medicine and Medical Device Development. This advancement is poised to revolutionize biomarker-based drug development for new immunotherapies, antibody drug conjugates, and paving the way for the analysis of the next generation of targeted cancer therapies.

Accepted Abstracts at ASCO 2024

PathAI will be attending and presenting abstracts at the upcoming ASCO event in Chicago, IL. Visit PathAIs booth in the Innovation Hub (IH18) May 31- June 4, 2024 to meet our team, learn more about AI-powered pathology, and engage with our scientists and collaborators at their respective posters.

Abstract #

Title

8539

Correlation of immune phenotypes derived from H&E-stained whole slide images with prognosis and response to checkpoint inhibitors in NSCLC.

4519

Association of machine learning (ML)derived histological features with transcriptomic molecular subtypes in advanced renal cell carcinoma (RCC).

Footnotes

1 PathExplore IOP and IHC Explore are for research use only. Not for use in diagnostic procedures.

About PathAI

PathAI is the leading precision pathology company providing software and AI-enabled solutions to all pathologist stakeholders including laboratories, research institutions, and the biopharma industry. Developed with the input of hundreds of pathologists, PathAIs digital pathology Image Management System, AISight, is the solution of choice for laboratories transitioning to digital workflows. Rigorously trained and validated with data from more than 15 million annotations, its AI-powered models can be leveraged to optimize the analysis of pathology samples to improve efficiency and accuracy of pathology interpretation, as well as to better gauge therapeutic efficacy and accelerate drug development for complex diseases. For more information, please visit www.pathai.com.

Contact Details

SVM Public Relations and Marketing Communications

Maggie Naples

+1 401-490-9700

pathai@svmpr.com

Company Website

https://www.pathai.com/

View source version on newsdirect.com: https://newsdirect.com/news/pathai-expands-portfolio-of-ai-powered-products-announcing-pathexplore-iop-and-ihc-explore-ahead-of-asco-2024-944684717

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Thunderball Results: Your Ultimate Destination for Real-Time Updates and Insights

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Thunderball is proud to announce itself as the ultimate online destination for thunder ball enthusiasts, offering the latest and most accurate results immediately after every draw. Whether you’re a regular follower or an occasional visitor. At thunderball results, we have a singular mission to ensure that Thunderball enthusiasts have easy access to the most recent and comprehensive results. It is designed with you in mind. We understand that the thrill of the game doesn’t just come from playing, it comes from waiting with bated breath for the results, and we make sure that wait is as short and stress-free as possible.

With the growing number of websites providing information on the internet, what sets us apart is our dedication to delivering accurate, timely, and accessible updates. We know how frustrating it can be to scour the web for reliable information or to miss out due to delays. That’s why our team works diligently to update results immediately, ensuring you have access to the latest information in real-time. 

Moreover, our platform offers more than just the most recent numbers. We provide a comprehensive archive of past Thunderball draws, allowing users to track patterns, revisit results, and strategize their future plays. 

What You Can Expect from us;

1. Timely Updates: One of the standout features of our platform is our commitment to offering timely updates immediately after each Thunderball draw. Our team stays on top of every draw, ensuring the winning numbers are posted on the site as soon as they are available. Say goodbye to long waits and misinformation—we deliver accurate results, fast.

2. Expert Analysis: We believe that informed players are better players. That’s why Thunderball results goes beyond the numbers to offer detailed analysis and valuable insights. Our expert team provides in-depth statistical breakdowns, offering users a chance to understand trends, hot numbers, and other factors that could impact future games.

A User-Friendly Experience

Our website has been designed with simplicity and efficiency at its core, so players of all levels can find what they need quickly and without hassle.  

We’ve also optimized the platform for mobile use, so whether you’re at home, commuting, or out with friends, you can check the latest results and never miss a moment of the action. As part of our commitment to accessibility, Thunderball Result is compatible with all devices, ensuring you can stay connected wherever you are.

About Thunderball 

Founded with the mission of creating an online hub for thunderball enthusiasts, Thunderball results has rapidly become the go-to destination for lottery players across the UK. We recognize that the key to a satisfying lottery experience is reliability, and our platform reflects that commitment through real-time updates, comprehensive data archives, and in-depth insights.

Our team is made up of passionate lottery fans and tech experts who understand the importance of providing quick and accurate information. Since launching, Thunderball Results has garnered a loyal following by consistently delivering results in a timely and efficient manner, making it a trusted resource for thousands of players every day.

At Thunderball Results, we’re more than just a results platform—we’re a community built around the excitement of the thunderball game. Whether you participate regularly or just enjoy checking the results, we invite you to join us to stay up to date with the latest thunderball draws and immerse yourself in a supportive and engaging community. For more information, visit https://thunderballresults.uk and follow us on social media for the latest news, updates, and winning numbers.

Contact details 

Company name: Thunderball Results 

Website link: https://thunderballresults.uk  

Contact email: info@thunderballresults.uk  

Country: United Kingdom 

City: London 

Contact person name: Thomas Ferguson

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Champ, America’s Loch Ness Monster ‘spotted’ in drone footage from filmmakers

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Champ, is that you?

Since the 1600’s, tales of a mysterious sea serpent named Champ, named after explorer Samuel de Champlain, have been part of the folklore of the Lake Champlain region. The lake borders New York and Vermont. Champlain and the Abenaki tribe were the first sightings of Champ in the historical record.

Champ remained elusive. The only notable visual evidence was a photo taken in 1977 by Sandra Mansi.

Until now.  For the first time in history, a video that allegedly captures the legendary lake monster on film is being hailed as the “most notable visual evidence” of Champ. Some compare it’s impact to the Patterson-Gimlin film impact on the Bigfoot cryptozoology community.

Independent filmmakers Kelly Tabor and Richard Rossi were shooting a fictional film ‘Lucy and the Lake Monster’ about a 9-year-old girl and her grandfather looking for Champ, a legendary lake monster rumored to live and lurk in the murky waters of Lake Champlain.  The film is based on their bestselling book of the same title.

As part of their shoot, their cameraman sent a drone above the lake in Bulwagga Bay, and what they saw in post-production stunned them.

They posted ten seconds of what is now known as the Tabor-Rossi footage on YouTube and 36,000 views later, it has provoked discussion and debate about what appears to some to be a plesiosaur swimming below the lake’s surface, behind a boat containing the two lead actors in their film, Emma Pearson and Richard Rossi.  The footage of the plesiosaur can be seen here: https://www.youtube.com/watch?v=Dkpzfqlt3PI.

(Plesiosaurs are a sea creature from the dinosaur-dominated Mesozoic era.)

Tabor and Rossi’s recent interview on the Cryptid Creature podcast was posted on Spotify. The duo submitted their footage and story for assessment by the two hosts, Todd Stevens and Brian Brock.  Stevens eloquently summed up his conclusion, affirming the veracity of the footage.

“The creature is bigger than the boat, fifty yards behind the boat, Stevens said.  “It has a plesiosaur body. It is not sturgeon, or multiple sturgeon. It is one large body moving.” The entire Cryptid Creatures interview with Tabor and Rossi can be heard here: https://play.cdnstream1.com/s/streamkastplus/cryptid-creatures/the-lake-champlain-monst-5a5bbe

Tabor first spotted the creature in the footage, editing on her large screen T.V.  “It’s poetic that Kelly saw it first,” Rossi said. “She has been looking for Champ for over fifty years.” Tabor grew up in a cabin on Lake Champlain in Crown Point, New York.

“We inadvertently caught this on camera,” Tabor said. “We weren’t trying to.”

If Kelly Tabor is the true believer of the screenwriting team, her writing partner Richard Rossi is the Doubting Thomas, insisting on the footage being evaluated by scientists with a doctorate in science and to prepare a report for peer review in 2025.

“I’m the more skeptical one compared to Kelly,” Rossi said.  “But there’s definitely something there.”

The filmmaking crew was so busy filming the movie, they didn’t catch the anomaly in the footage until later, in the post-production editing stage.

Multiple versions of their footage are now on Pinterest and YouTube as cryptozoologists use their tech savvy to zoom in on the Champ image, and use coloring to do morphological enhancements and evaluations.  

The Tabor-Rossi Champ footage is incorporated into their fictional film, ‘Lucy and the Lake Monster,’ at about the four-minute mark of the film. The movie has screened in theaters in New York, New Jersey, Vermont, Pennsylvania, California, and South Carolina.  This month, it won 12 awards in film festivals.  It will be released on DVD and streaming next year.

“As filmmakers, our primary focus is on the art form itself.  We don’t respond too much to the debate around the footage,” Rossi said. “We try to focus on doing the best job we can in our screenwriting, acting, cinematography, and music.  It’s nice that Champ has blessed us with the benefits of headlines that let people know about our book and the film, but at the end of the day, our focus is on showing the film and writing the next sequel. Champ has been a great publicist.”

“Champ is also one of the biggest stars in our new film,” Tabor added.

Media Contact:

Reporter Christy Collins

richardrossilive@gmail.com

https://www.lucyandthelakemonster.com/ 

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This December, Meet Barracuda Coin The Next Big Crypto

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Since its inception in February 2023, Barracuda Coin has been preparing for a highly anticipated launch, positioning itself as a prominent player in both the cryptocurrency and sports sectors. Backed by significant sponsorship deals with numerous sports events, Barracuda Coin is poised to make an impactful entrance into the crypto space, aligning itself with the competitive energy of professional sports.

Ethereum-Based Token with a Strong Focus on Sports

Barracuda Coin is built on the robust Ethereum blockchain, ensuring security and reliability for all transactions. With a total supply of 75,000,000 tokens, Barracuda Coin is already gaining traction through its involvement in MMA and K1 sports sponsorships and has established itself as a key sponsor for numerous professional sports events.

In tandem with the coin’s launch, Barracuda Coin will release a unique NFT collection featuring high-performing athletes, giving fans and collectors a unique opportunity to own exclusive digital assets tied to their favorite sports icons.

Staking Program for Early Investors

To reward early supporters, Barracuda Coin is launching an attractive staking program with two levels of rewards:

  • Investors who join during the reservation phase will receive 75% monthly interest for 6 months.
  • Those participating in the presale will enjoy a 30% monthly interest over the same period.

Important Dates and Pricing

  • Reservation Phase: Beginning on November 4, 2024, and running through November 28, 2024, the price per Barracuda Coin (BARR) during this period will be $0.019.
  • Presale Phase: After the reservation period ends, the presale will begin at $0.05 per token, gradually increasing up to $0.15.
  • Official Launch: Scheduled for December 23, 2024, with the token price projected to reach $0.36.

Barracuda Coin and Pay-Per-View Entertainment

Designed with the entertainment and sports industry in mind, Barracuda Coin is set to seamlessly integrate with the pay-per-view model, making it the ideal token for fans. With fast, secure, and transparent transactions, Barracuda Coin will allow users to easily access premium sports content and live events, bypassing the challenges of traditional currency exchanges.

About Barracuda Coin

Barracuda Coin is more than a cryptocurrency; it’s a platform connecting the worlds of sports, crypto, and digital assets. Focused on creating a space for sports enthusiasts, collectors, and investors alike, Barracuda Coin offers a comprehensive platform that includes a strong staking program, an exclusive NFT collection, and seamless integration with pay-per-view sports. With these innovative offerings, Barracuda Coin is set to establish itself as a leader in both the cryptocurrency and entertainment sectors.

Register and Be Part of the Barracuda Coin Community

Investors are encouraged to participate in the reservation phase to secure tokens at the lowest price and maximize staking rewards. For more information, visit https://barracuda-coin.io/

Media Contact:

Barracuda Coin

support@barracuda-coin.io

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