Press Release
Oncotelic Therapeutics (OTC: OTLC) Inks Deal With Mosaic ImmunoEngineering To Sell Clinical-Stage Necroptosis Cancer Therapy Assets
–News Direct–
By Faith Ashmore, Benzinga
The global retinoblastoma treatment market size was estimated to be $2.62 billion in 2023 and is expected to reach $4.20 billion by 2034 with a CAGR of 4.38% over 2024-2034. Rising incidence of retinoblastoma, early diagnosis and treatment, increasing healthcare expenditure, growing awareness of retinoblastoma treatment options, development of new treatments and government initiatives will drive the markets growth.
Recently, the FDA granted accelerated approval to Iovance Biotherapeutics (NASDAQ: IOVA) lifileucel (Amtagvi) to treat inoperable or metastatic melanoma, making it the first and only one-time tumor-infiltrating lymphocyte (TIL) therapy to be greenlighted for solid tumors. Lifileucel is manufactured by collecting and expanding a patients unique T cells from part of their tumor and then infusing them into that patient to fight the cancer.
Oncotelic Therapeutics (OTCQB: OTLC) is looking to develop similar treatment therapies for ocular cancers, including retinoblastoma and uveal melanoma. The technology is named necroptosis therapies.
Oncotelic and Mosaic ImmunoEngineering, Inc. (OTC: CPMV) are developers of necroptosis therapies. The recent approval of TIL cell therapy demonstrates how to manipulate patient immunity against cancer for a lasting cure. However, TIL cell therapy is costly, time-consuming and technologically challenging. Instead of driving TIL cells externally, Necroptosis Cancer Therapies drive innate TILs to the tumor. The key step is the induction of necrotic cell death and activation of death genes, exposing tumor-reactive antigens to initiate an immune response, activating antigen-presenting cells to achieve large-scale antigen presentation, activating T-cells, inducing strong and sustained cytotoxic T lymphocyte responses, and ultimately triggering a TIL antitumor immune effect. Necroptosis Cancer Therapies can use vascular disrupting agents (VDA), in combination with CheckPoint Inhibitors and other IO agents to drive TIL cells to the tumor.
Oncotelic Therapeutics recently announced a binding term-sheet agreement with Mosaic ImmunoEngineering. Under this arrangement, Mosaic will acquire the rights to Oncotelic's clinical-stage necroptosis cancer therapies. These innovative therapeutics disrupt tumor blood flow, leading to immunogenic tumor cell death through the activation of "death receptors" ultimately triggering a potent anti-cancer immune response. As part of the deal, Mosaic will also gain access to Oncotelic's AI technologies for identifying immunotherapy combinations.
"We are very pleased to have this opportunity to bring these clinical stage assets that have promise for the treatment of multiple types of cancer into Mosaic. We anticipate that the initial application of the technology will be in areas with high unmet medical need such as uveal melanoma and retinoblastoma. We look forward to working with the Oncotelic team to advance the program," said Steven King, President and CEO of Mosaic.
As outlined in the binding term sheet, Mosaic will issue $15 million in CPMV shares to Oncotelic upon the execution of the definitive purchase agreement. Additional milestones will enable Oncotelic to earn up to an extra $15 million in CPMV shares. The experienced Mosaic team, with a collective background encompassing more than 30 FDA and worldwide product approvals, will spearhead the advancement of these technologies. Both companies will collaborate closely to ensure the smooth transfer of technologies from Oncotelic to Mosaic, with Oncotelic providing short-term financial support for the program while working together toward achieving short-term and long-term financing goals.
"This will be the second transaction for capitalizing on our assets and building shareholder value. The first being the successful transition of OT-101 to our joint venture (JV) with Dragon Capital Overseas, Limited. The JV is expected to list for an IPO and has been expanding its R&D including the completion of its research and manufacturing facility headquartered in San Diego, California." shared Dr. Vuong Trieu, CEO of Oncotelic.
Pipeline What More To Expect From Oncotelic
Oncotelic has multiple drugs in its pipeline, such as ArtiVeda/ArtiShield, a COVID drug that aims to inhibit the spread of the virus; OT-101 for the treatment of solid tumors with a focus on brain cancer in adults and diffuse intrinsic pontine glioma in children; CA4P, which is intended to be used with Ipilimumab for the treatment of solid tumors with focus on melanoma; Oxi4503 for the treatment of liquid tumors with focus on childhood leukemia; and AL-101, an intranasal drug for the treatment of Parkinson Disease that also targets Erectile Dysfunction and Female Sexual Dysfunction. Oncotelic is looking to develop these drugs using a similar JV structure, which should enhance shareholder values.
With an encouraging recent announcement and an extensive pipeline, Oncotelic may be a company to watch as it continues its endeavors to provide patients with more efficient treatments with fewer side effects.
Featured photo by Olga Kononenko on Unsplash.
Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders.
This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice.
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View source version on newsdirect.com: https://newsdirect.com/news/oncotelic-therapeutics-otc-otlc-inks-deal-with-mosaic-immunoengineering-to-sell-clinical-stage-necroptosis-cancer-therapy-assets-350987041
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Press Release
Prompt Passport Services Offers Expedited Passport Renewal Services for US Citizens in New Hampshire
Prompt Passport Services: Fast and Secure Passport Solutions for Emergency Travel Needs
Philadelphia, PA, 27th November 2024, ZEX PR WIRE, Prompt Passport Services, a registered passport courier service renowned for its secure and efficient processes, is excited to announce the availability of expedited passport renewal services for US citizens in New Hampshire. These services are specifically designed to address urgent travel needs and emergencies, ensuring a smooth and reliable experience for customers.
With international travel on the rise and the holiday season nearing, the demand for quick and hassle-free passport renewals has surged. Prompt Passport Services is stepping up to meet this need, offering tailored solutions that prioritize speed, security, and customer satisfaction.
The company’s expedited renewal services come with a host of benefits:
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Rapid Processing: Renewals can be completed in as little as 24 hours in qualifying situations, making this service ideal for emergency travel needs.
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Personalized Support: Each customer is paired with a dedicated account manager who ensures all documentation is completed accurately and on time.
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Flexibility and Convenience: Services are available both in-person and remotely, catering to the preferences and schedules of New Hampshire residents.
Prompt Passport Services’ efficient process is backed by a secure system designed to protect personal information while ensuring rapid delivery of passports. By offering these specialized services, the company remains committed to easing the stress of last-minute travel requirements.
David Smith, Regional Operations Manager at Prompt Passport Services, highlighted the company’s focus on customer satisfaction. “We’re here to simplify the passport process for travelers in New Hampshire. Our expertise and dedication to efficiency help our customers feel confident that their travel plans won’t be derailed by documentation delays.”
Residents looking to renew their passports quickly can contact Prompt Passport Services directly or visit the company’s website for detailed instructions and resources. The website offers step-by-step guidance and transparency about processing times, ensuring a worry-free experience for all.
Prompt Passport Services is dedicated to meeting the needs of travelers nationwide. Its reputation for fast and secure passport solutions has made it a trusted partner for individuals and families planning trips abroad.
About Prompt Passport Services
Prompt Passport Services is a trusted provider of expedited passport and visa services across the United States. Specializing in new passport applications, child passport processing, passport renewals, and urgent travel needs, the company offers fast, secure, and reliable solutions tailored to each customer. With a dedicated account manager for every client and both in-person and remote support options, Prompt Passport Services ensures a seamless and stress-free experience for all travelers.
Contact Information:
Website: https://www.usonlinepassports.com/
Phone: 215-397-1135
Address: 2035 W Ritner St, Philadelphia, PA 19145
Facebook: https://www.facebook.com/people/Prompt-Passport-Service/100065142685707/
YouTube: https://www.youtube.com/channel/UCuRM0_ZQ0WJkz6AQsEPbIDg
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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
United States, 27th Nov 2024 – In an exciting new development for travelers seeking a personalized, stress-free vacation to Costa Rica, My Costa Rica, a leading tour operator, and CostaRica.Org, its U.S.-based counterpart, have enhanced their services to offer even more exclusive deals, local expertise, and comprehensive travel planning to clients worldwide.
Since its inception in 2004, My Costa Rica has been a trusted name in planning unforgettable vacations to one of the most biodiverse countries on the planet. The company’s reputation for excellence has been solidified by its accreditation from the Costa Rican Tourism Board (ICT) and the Costa Rican Chamber of Tourism (CANATUR). To expand its reach and provide even greater convenience, CostaRica.Org was established in Colorado in 2019, offering U.S. customers direct access to the same exceptional service and insider knowledge that has made My Costa Rica a top choice for Costa Rican travel.
No Extra Fees, Just Better Deals
One of the standout features of My Costa Rica’s services is that booking a vacation through the agency costs no more than doing it yourself. With no additional fees for their travel planning services, My Costa Rica helps travelers get the most value out of their Costa Rican getaway. The agency’s team is well-versed in finding the best seasonal specials, discounts, and promotions, ensuring clients enjoy an affordable vacation with exclusive perks.
“My Costa Rica offers something truly unique: expertise and cost-saving opportunities for every traveler,” said Jason Bateman, the spokesperson for the company. “We are passionate about showcasing all that Costa Rica has to offer—from its world-renowned beaches to its lush rainforests—and doing so at the best possible price.”
A Wealth of Knowledge at Your Fingertips
Costa Rica is renowned for its natural beauty, diverse ecosystems, and adventure-filled offerings, including pristine beaches, volcanoes, and exotic wildlife. My Costa Rica’s expert team tailors each itinerary to meet individual preferences, from adrenaline-filled tours of the best attractions in Costa Rica to relaxing vacations on the nicest beaches in Costa Rica. The agency’s deep knowledge of the local landscape allows them to provide clients with an authentic, off-the-beaten-path experience, all while ensuring a seamless, enjoyable vacation.
“We don’t just book vacations; we craft experiences,” added Bateman. “Whether travelers are looking for a luxury getaway, a family-friendly adventure, or a secluded nature retreat, our team has the expertise to make it happen.”
Expanding Access to the USA
Since opening CostaRica.Org in Colorado, the agency has made it easier for U.S.-based clients to plan their dream vacations without navigating complex booking platforms or worrying about hidden fees. The new agency offers the same excellent services and local expertise, ensuring that customers on both sides of the border have access to the best that Costa Rica has to offer.
A Sustainable Future for Costa Rica Travel
My Costa Rica and CostaRica.Org are committed to sustainable travel practices, helping travelers explore Costa Rica responsibly. The agency works with eco-friendly hotels, tour operators, and transportation providers, ensuring that each vacation has a minimal environmental impact while still delivering a world-class experience.
For more information on how My Costa Rica can help you plan your Costa Rican escape, visit CostaRica.Org or reach out via email at info@costarica.org. Stay updated by following the company on LinkedIn, Facebook, and X (formerly Twitter).
About My Costa Rica & CostaRica.Org
My Costa Rica and CostaRica.Org are part of an international team of travel professionals dedicated to providing unparalleled vacation experiences in Costa Rica. Founded in 2004, My Costa Rica is a premier tour operator based in San Jose, Costa Rica, offering expert travel planning services for individuals, families, and groups. The company is accredited by the Costa Rican Tourism Board (ICT) and the Costa Rican Chamber of Tourism (CANATUR), and is recognized for its commitment to exceptional customer service, sustainable tourism, and local expertise.
In 2019, CostaRica.Org was launched in Colorado to make Costa Rican travel even more accessible to U.S.-based clients. The agency provides personalized travel planning with no additional fees, offering exclusive deals and seasonal discounts. With a deep understanding of Costa Rica’s attractions, culture, and natural wonders, the team works closely with clients to curate the perfect itinerary for every traveler. Whether it’s a romantic getaway, family adventure, or corporate retreat, My Costa Rica and CostaRica.Org strive to exceed every traveler’s expectations.
Media Contact
Organization: My Costa Rica
Contact Person: Jason Bateman
Website: https://costarica.org/
Email: Send Email
Country: United States
Release Id: 27112420350
The post My Costa Rica and CostaRica.Org Expand Services to Help Travelers Explore Costa Rica appeared on King Newswire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.
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Press Release
Ambassador Global Chauffeur Offers Luxury Group Shuttle Bus Services for Corporate Clients in Atlanta
New shuttle service brings unmatched comfort and professionalism to corporate transportation needs.
Georgia, US, 27th November 2024, ZEX PR WIRE, Ambassador Global Chauffeur, a leader in premium transportation, is proud to introduce its luxury shuttle bus service tailored specifically for corporate clients throughout the Atlanta area. This new service caters to large corporate groups and is designed to elevate the group transportation experience, combining comfort, convenience, and efficiency with the refined service Ambassador Global Chauffeur is known for.
With Atlanta’s status as a bustling business hub, the demand for upscale, reliable group transportation solutions continues to grow. Ambassador Global Chauffeur’s shuttle service provides companies with a sophisticated, hassle-free way to transport employees, clients, and executives, whether it’s for airport transfers, conferences, business retreats, or off-site meetings. Each shuttle is equipped with high-end leather seating, climate control, and modern amenities like complimentary Wi-Fi, charging ports, and plenty of storage space to support productivity and comfort on the go.
Ambassador Global Chauffeur’s shuttle service prioritizes both luxury and functionality, offering businesses a seamless solution that combines professionalism with convenience. By opting for the company’s new shuttle service, corporate clients can make a lasting impression, ensuring their guests travel in comfort, style, and on schedule.
“Our corporate shuttle service is designed with a singular goal in mind: to provide Atlanta’s business community with an unparalleled group transportation experience,” said James Robertson, CEO of Ambassador Global Chauffeur. “Whether it’s a team retreat or a VIP client meeting, we understand that quality transportation reflects on the company. Our luxury shuttles allow our clients to focus on their business while we handle every detail of their transportation needs with precision and dedication.”
Ambassador Global Chauffeur’s team of professionally trained chauffeurs is committed to providing a smooth and dependable experience. Every chauffeur is well-versed in Atlanta’s routes, business districts, and traffic patterns, ensuring clients arrive at their destinations promptly and stress-free. This level of attentiveness and expertise is part of the company’s commitment to setting the highest standards in transportation services.
With the introduction of this luxury shuttle service, Ambassador Global Chauffeur continues to meet the evolving needs of its corporate clientele. Businesses now have a customizable, high-quality solution for group transportation that mirrors the sophistication and professionalism their brand demands. The shuttle service is flexible, with tailored schedules and routes to accommodate each client’s unique requirements, setting a new benchmark for group travel in Atlanta.
About Ambassador Global Chauffeur
Ambassador Global Chauffeur is a premier provider of luxury transportation solutions in Atlanta, specializing in high-quality services for corporate, private, and group travel needs. With a dedication to comfort, punctuality, and professionalism, the company offers an array of services, including airport transfers, business transportation, event shuttles, and private tours. Ambassador Global Chauffeur’s fleet features meticulously maintained vehicles, each driven by experienced, courteous chauffeurs who prioritize customer satisfaction and safety.
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Disclaimer: The views, suggestions, and opinions expressed here are the sole responsibility of the experts. No Digi Observer journalist was involved in the writing and production of this article.
Prompt Passport Services Offers Expedited Passport Renewal Services for US Citizens in New Hampshire
My Costa Rica and CostaRica.Org Expand Services to Help Travelers Explore Costa Rica
Ambassador Global Chauffeur Offers Luxury Group Shuttle Bus Services for Corporate Clients in Atlanta
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