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MAIA Biotechnology’s Unique Telomere Targeting Agent Currently In Clinical Development Shows Promise For The Multi-Billion Dollar Cancer Therapy Market

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–News Direct–

By Kyle Anthony, Benzinga

MAIA Biotechnology (AMEX: MAIA) is a cutting-edge biopharmaceutical company dedicated to developing innovative therapies for cancer treatment. The companys mission is to discover, develop and deliver transformative cancer therapies that improve patients' lives worldwide. MAIA Biotechnology envisions a future where cancer is manageable and patients can live longer, healthier lives. The firm is at the forefront of revolutionizing oncology, leveraging advanced scientific research and technological advancements to drive its progress, with the goal of bringing treatments that target cancer's replication mechanism in a more efficacious and less harmful manner than traditional therapies.

Company Background

Founded in August 2018 and headquartered in Chicago, Illinois, MAIA Biotechnology is led by an experienced management team and supported by scientific advisors with extensive drug development experience who are committed to advancing promising agents into human clinical trials. MAIA Biotechnology specializes in telomere-targeting therapies for cancer treatment. As such, the firms current product focus is the development of first-in-class drugs that target proteins that control how cancer cells grow, divide and spread.

MAIA Biotechnology's pipeline includes several promising candidates in various stages of development, but its premier product offering is THIO (6-thio-2-deoxyguanosine), a first-in-class telomere-targeting agent designed to selectively kill telomerase-positive cancer cells, which are present in most human cancers.

The Role Of Telomeres In Cancer

Telomeres play a crucial role in cellular aging and cancer development. Research published by the Dana-Farber Cancer Institute explains that cancer cells often avoid senescence or cell death by rebuilding and maintaining their telomeres despite repeated cell divisions. This is possible because the cancer cells activate an enzyme called telomerase, which adds genetic units to the telomeres to prevent them from shortening to the point of causing cell death. As a result, cancer cells essentially become immortal. Telomerase is silenced in most normal cells but is active in an estimated 85% to 95% of human cancer cells.

Since telomerase is active in cancer cells but not normal cells, it is seen as a promising target for cancer therapy. Due to telomerase inhibition, activity or expression, telomere-targeting drugs might kill tumor cells by allowing telomeres to shrink or by provoking apoptosis, the process of programmed cell death.

By incorporating into telomeres, THIO disrupts their function, leading to cancer cell death. This approach has shown promising preclinical results and has been undergoing clinical trials.

Product Development Pipeline

THIO is MAIA Biotechnologys most advanced product offering, which has shown positive efficacy findings in treating advanced non-small cell lung cancer (NSCLC) in clinical trials. The ongoing clinical trial is testing the hypothesis that lower doses of THIO administered before immune checkpoint inhibitor Libtayo treatment (i.e., stimulation of the immune system to attack cancer cells) would enhance and prolong responses in subjects with advanced NSCLC who did not respond or progress after first-line treatment with a checkpoint inhibitor, a type of drug that blocks proteins called checkpoints that are made by some types of immune system cells such as T cells and some cancer cells. These checkpoints help keep immune responses from being too strong and sometimes can keep T cells from killing cancer cells.

The clinical trial's positive results support THIO's tolerability and safety as an anticancer therapy and a priming immune activator. Treatment with THIO sequenced with Libtayo treatment was found to be well-tolerated in a heavily pre-treated population thus far.

MAIA Biotechnology is also researching other drug treatments, using its expertise in telomere-targeting agents as a foundation. The companys second-generation program aims to discover new compounds with potentially improved specificity toward cancer cells relative to normal cells and potentially increased anticancer activity. This program will allow MAIA Biotechnology to strengthen its patent portfolio over time, which already has five issued patents and 29 applications pending worldwide.

Market Potential and Industry Impact

Research published by Coherent Market Insights estimates the cancer therapy market will be worth $205.10 billion in 2024 and is expected to reach $466.21 billion by 2031. The driving factors behind this growth are the rising occurrence of cancer worldwide and the increasing demand for cancer treatment.

As such, MAIA Biotechnologys THIO addresses a large and growing market. As outlined in their most recent corporate presentation, lung and colon cancer are the first and second most prevalent cancer types globally, respectively, and treating them specifically would generate billions in sales. Given the current opportunity, MAIA Biotechnology will continue to protect its intellectual property while expanding its patent portfolio. Recently, the Food and Drug Administration (FDA) granted a third orphan drug designation (ODD) to THIO as a treatment for glioblastoma; the drug also holds ODDs for hepatocellular carcinoma and small-cell lung cancer. The glioblastoma market is expected to grow from $2.2 billion to $3.2 billion globally in the next three years.

The FDAs ODD program provides multiple incentives to make orphan drug development more financially feasible for companies. These include up to seven years of market exclusivity for the approved orphan drug, up to 20 years of 25% federal tax credit for expenses incurred in conducting clinical research within the U.S., and waiver of Prescription Drug User Fee Act (PDUFA) fees for orphan drugs, a value of approximately $2.9 million in 2021.

Conclusion

MAIA Biotechnologys approach to cancer treatment differentiates it from its peers, potentially placing the company in a unique market position. As incidences of cancer continue to rise globally, drug treatment options, such as THIO, will likely rise in demand. As such, the benefit that MAIA Biotechnology provides and the value proposition the firm espouses will likely continue to have industry resonance.

Featured photo by National Cancer Institute on Unsplash.

Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders.

This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice.

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Crypto Crime Investigations Issues Urgent Advice: What to Do When a Digital Wallet Is Compromised

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Atlanta, Georgia – In the ever-evolving world of cryptocurrency, the security of digital wallets has become a pressing concern for users globally. As the market expands, so does the prevalence of cybercrime, making it essential for individuals to understand the steps to take if they suspect their cryptocurrency wallet has been compromised. Crypto Crime Investigations, a leading firm specializing in digital asset recovery and cybercrime investigations, is here to provide guidance.

With the rise in the use of cryptocurrencies, incidents of wallet hacking and fraud have surged, often leaving victims feeling 

helpless and uncertain about their next steps. Crypto Crime Investigations emphasizes that immediate action is crucial in mitigating losses and increasing the chances of recovery.

Immediate Steps to Take:

1. Stay Calm and Assess the Situation: If you notice unauthorized transactions or access to your wallet, take a deep breath. Panicking can lead to hasty decisions.

2. Secure Your Remaining Assets: If you have not already done so, transfer any remaining funds to a new wallet that is secured with strong passwords, two-factor authentication, and preferably a hardware wallet for added security.

3. Document Everything: Keep a detailed record of all transactions, communications, and any signs of unusual activity. This information will be invaluable during the investigation.

4. Notify Your Wallet Provider: Contact your wallet provider immediately. Many reputable services have protocols in place to assist users in the event of a security breach.

5. Report the Incident: File a report with the appropriate authorities. This may include local law enforcement and agencies specializing in cybercrime. Crypto Crime Investigations can assist with this process, providing expertise in navigating legal and regulatory frameworks.

6. Engage with Crypto Crime Investigations: Our team of experienced professionals specializes in tracing stolen assets and conducting thorough investigations. We utilize advanced forensic tools and collaborate with law enforcement to help recover lost funds and bring cybercriminals to justice.

7. Educate Yourself: Understanding the risks and security measures associated with cryptocurrency can prevent future incidents. Participate in workshops and follow updates from trusted sources within the crypto community.

Prevention is Key

The best strategy against crypto crime is prevention. Crypto Crime Investigations advocates for implementing robust security practices, such as using hardware wallets, enabling two-factor authentication, and regularly updating passwords.

As the landscape of digital currencies continues to grow, so does the importance of vigilance and education within the community. Crypto Crime Investigations remains committed to supporting individuals and businesses in safeguarding their digital assets.

For more information on how to protect yourself and your assets, or if you need assistance following a security breach, please visit our website at http://www.cryptocrimeinvestigations.com or contact us directly info@cryptocrimeinvestigataion.com .

About Crypto Crime Investigations

Crypto Crime Investigation is a premier agency dedicated to combating cybercrime within the cryptocurrency space. Our team of experts is passionate about helping victims recover lost assets and educating the public on best practices for securing digital wallets. We leverage cutting-edge technology and extensive industry experience to navigate the complexities of crypto-related investigations.

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Organization: Crypto Crime Investigations

Contact Person: Daniel Johnson   Public Relations Manager

Website: http://www.cryptocrimeinvestigations.com/

Email: Send Email

Country: United States

Release Id: 26102419047

The post Crypto Crime Investigations Issues Urgent Advice: What to Do When a Digital Wallet Is Compromised appeared on King Newswire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.

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St. Paul’s PACE Hosts Workshops and Tours at 2024 National PACE Association Conference

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San Diego, Calif. (October 25, 2024)– St. Paul’s PACE – Program of All-Inclusive Care for the Elderly –attended the 2024 National PACE Association (NPA) Annual Conference hosted at the Manchester Grand Hyatt San Diego. The dynamic four-day event provided St. Paul’s PACE leadership an opportunity to network with PACE programs from across the country and gather insights to enhance their services.

“The relationships we form and the tools we gain here will directly impact our approach to care moving forward,” said Shravan Mupparapu, Vice President of PACE Services at St. Paul’s PACE. “By collaborating with other PACE programs and learning from their experiences, we can create new pathways for innovation that shape the future of St. Paul’s PACE.”

St. Paul’s PACE leadership team at 2024 NPA Conference

This year’s conference placed an emphasis on behavioral health for PACE staff and participants. Other focus areas included quality improvement strategies, nursing practices, and effective intake techniques, which were explored through several educational sessions. Dr. Jacob Paulsen, Behavioral Health Program Manager for St. Paul’s PACE, hosted a workshop on behavioral health, discussing the need for innovative care strategies that address the unique challenges participants are facing.

Dr. Jacob Paulsen, Behavioral Health Program Manager for St. Paul’s PACE, hosts a workshop on behavioral health strategies.

“The traditional spectrum of care often falls short for our participants,” said Dr. Paulsen. “As experts in this field, we need to be creative in our approaches and deliver flexible, individualized care, especially when treating participants struggling with substance abuse and psychotic disorders.”

Leaders from visiting PACE programs gather for a tour of PACE Akaloa in Chula Vista

Throughout the conference, St. Paul’s staff hosted tours of their Chula Vista center, PACE Akaloa, for over 180 health professionals visiting from other PACE programs. The tours highlighted Akaloa’s unique approach to serving the diverse needs of its participants, the majority of whom are Spanish-speaking.

St. Paul’s involvement in this year’s NPA conference demonstrated its ongoing commitment to fostering collaboration and prioritizing innovation in senior care. By leveraging the knowledge gained, St. Paul’s PACE aims to deliver even higher-quality care to its participants.

St. Paul’s PACE supports seniors so they can continue to live independently at home by providing personalized medical services, social services, transportation, and home care. Seniors who are over 55 years years old with chronic medical conditions that make it difficult to live at home may qualify for services. For more information on St. Paul’s PACE, visit StPaulsPACE.org or call 1(833) PACE NOW. Press contact:  Nicole Antonacci, St. Paul’s Senior Services Communications Specialist, 619-239-6900

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Organization: St. Paul’s PACE

Contact Person: Nicole Antonacci

Website: https://www.stpaulspace.org

Email: Send Email

Contact Number: +16195517400

Address: 1306 Broadway

City: El Cajon

State: CA

Country: United States

Release Id: 26102419033

The post St. Paul’s PACE Hosts Workshops and Tours at 2024 National PACE Association Conference appeared on King Newswire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.

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Advisor Wechat Capital Spirit of Discovery

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Advisor Wechat Capital (AWC), a pioneer in digital asset management, is redefining the future of finance by integrating cutting-edge technologies into its investment strategies. Positioned at the forefront of digital finance, AWC recognizes the transformative power of digital assets and blockchain technologies, positioning itself as a key player in an increasingly digital world. As part of its commitment to future growth, AWC is embarking on an extensive global expansion, aiming to grow its investment portfolio, recruit top talent worldwide, and forge partnerships with leading enterprises and academic institutions.

Advisor Wechat Capital (AWC), a pioneer in digital asset management, is redefining the future of finance by integrating cutting-edge technologies into its investment strategies. Positioned at the forefront of digital finance, AWC recognizes the transformative power of digital assets and blockchain technologies, positioning itself as a key player in an increasingly digital world. As part of its commitment to future growth, AWC is embarking on an extensive global expansion, aiming to grow its investment portfolio, recruit top talent worldwide, and forge partnerships with leading enterprises and academic institutions.

The Global Surge of Digital Assets

In recent years, digital assets have surged in popularity and value, no longer confined to niche circles but widely recognized across mainstream finance. Cryptocurrencies, non-fungible tokens (NFTs), and blockchain innovations are now integral to investment strategies and financial growth. Advisor Wechat Capital has not only embraced this evolution but has positioned itself as a leader in integrating digital assets into conventional portfolios. By offering access to these emerging assets, AWC enables investors to diversify while capturing the benefits of this growing sector.

Integrating Blockchain for Enhanced Security and Transparency

Blockchain technology serves as the foundation for many of today’s digital assets, and AWC is leveraging it to provide secure, transparent, and efficient financial services. By incorporating blockchain into its operational infrastructure, AWC achieves a new level of transaction transparency and security, significantly reducing risks compared to traditional finance models. AWC’s commitment to adopting blockchain solutions demonstrates a proactive approach to safeguarding investments while delivering top-tier service. Its blockchain-driven offerings allow investors to benefit from high security, transparency, and reduced transaction costs.

Expanding Investments and Partnerships Worldwide

AWC’s expansion strategy is designed to meet the growing global demand for digital assets and blockchain-backed services. As part of this strategy, AWC is significantly increasing its international footprint, reaching new markets and forging alliances with established enterprises and top universities. By partnering with innovative companies and educational institutions, AWC not only fosters innovation but also ensures a steady pipeline of qualified professionals who are adept in blockchain and digital finance. This collaborative approach underscores AWC’s mission to bring the benefits of digital asset management to a global audience.

Through these partnerships, AWC intends to:

  • Strengthen Innovation: Collaborating with enterprises to co-develop blockchain applications and asset management solutions.
  • Support Talent Development: Partnering with universities to offer internships, research opportunities, and specialized training programs in blockchain and digital finance.
  • Promote Thought Leadership: Hosting seminars, conferences, and webinars to advance the knowledge and application of digital assets and emerging financial technologies.

Investing in Talent: A Global Initiative

AWC’s success relies on the expertise and forward-thinking approach of its team, and it is committed to recruiting the best talent worldwide. This recruitment drive focuses on individuals with diverse skill sets in blockchain, financial analysis, digital asset management, and data science. AWC values innovation, dedication, and adaptability, and its hiring strategy aims to foster a work culture that attracts and retains top professionals in the industry.

The talent initiative includes:

  • Global Recruitment: Sourcing skilled professionals from around the world to strengthen AWC’s global presence and bring diverse perspectives to the team.
  • Ongoing Training: Offering continuous learning opportunities, certifications, and specialized training programs that keep employees at the forefront of the industry.
  • Collaborative Learning: Partnering with universities for mentorship programs and hands-on training, helping students and recent graduates develop skills directly relevant to careers in digital finance.

Educating Investors: AWC’s Commitment to Client Empowerment

AWC recognizes that while digital assets present exciting new opportunities, they can be complex for those more accustomed to traditional investments. To address this, AWC is deeply committed to investor education. Through its comprehensive programs—including webinars, guides, and individual consultations—AWC ensures that its clients are well-informed and confident in their investment decisions. This commitment to education not only empowers investors but also contributes to the industry’s growth by helping people understand and navigate the digital finance landscape.

Conclusion: AWC’s Vision for the Future of Finance

As the financial world undergoes a digital transformation, Advisor Wechat Capital is leading the way, not just by adopting new technologies but by actively shaping the future of asset management. Through its global expansion, recruitment efforts, and partnerships with enterprises and universities, AWC is creating a sustainable, innovation-driven ecosystem that benefits investors and the digital finance community alike. AWC’s proactive approach, integrating blockchain, digital assets, and a global talent base, positions it as a trailblazer in digital asset management.

For more information on Advisor Wechat Capital and its innovative approach to digital finance, visit advwechat.com.

Media Contact

Organization: Advisor Wechat Capital

Contact Person: Spencer Brown

Website: https://www.advwechat.com/#/

Email: Send Email

Address: 600 17th St, Denver, CO 80202, USA

Country: United States

Release Id: 26102419061

The post Advisor Wechat Capital Spirit of Discovery appeared on King Newswire. It is provided by a third-party content provider. King Newswire makes no warranties or representations in connection with it.

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